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Detection ofBorrelia burgdorferi by nested polymerase chain reaction in cerebrospinal fluid and urine of children with neuroborreliosis (1993)

Huppertz, H. -I. ; Schmidt, H. ; Karch, H.

Springer

European journal of pediatrics 152 (1993), S. 414-417

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ISSN: 1432-1076

Keywords: Neuroborreliosis ; Borrelia burgdorferi ; Polymerase chain reaction

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Diagnosis of neuroborreliosis is often difficult since history and clinical presentation may be non-specific and serological tests may initially be negative. We therefore tested the polymerase chain reaction (PCR) for the detection of borrelial sequences in CSF and urine samples of consecutive children with neuroborreliosis seen in a single summer season. Four of eight children were negative in serum for antibodies toBorrelia burgdorferi. Two of eight children were PCR-positive in CSF and one other child was positive in urine. In two out of four children PCR was the only laboratory test confirming the clinical diagnosis. All children recovered after treatment with third generation cephalosporins. When seven of eight children were re-examined 6 months later all were healthy and antibodies toB. burgdorferi were detected in their serum. PCR may assist the paediatrician in establishing a diagnosis of neuroborreliosis; however, a negative result does not rule out neuroborreliosis. PCR is an adjunct, but no substitute for clinical judgement and serology.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01955900

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Reinforcement of amorphous thermoplastics by blending with a para-linked aromatic LC-polyester (1990)

Claßen, M. S. ; Schmidt, H.-W. ; Wendorff, J. H.

New York, NY : Wiley-Blackwell

Polymers for Advanced Technologies 1 (1990), S. 143-150

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ISSN: 1042-7147

Keywords: Reinforcement ; Amorphous ; Matrix ; LC-polyester ; Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

Notes: The preparation and the mechanical properties of binary blends of amorphous thermoplastics and a para-linked liquid crystalline polyester, which is expected to act as a reinforcement, are reported. The LC-polyester has the advantage that it is soluble in common organic solvents, that it has a low transition temperature, and that it does not crystallize readily. Polycarbonate, polystyrene, poly(methyl methacrylate), and poly(ether sulfone) were selected as matrix materials. Most of the films cast from the blends turned out to be turbid and thus phase separated, the sizes of the dispersed phases ranging between 0.2 μm (in polycarbonate) and 1 μm (in polystyrene).The LC-polyester causes a substantial increase of the stiffness in blends with polycarbonate, poly(methyl methacrylate), and poly(ether sulfone) and almost no increase in the case of polystyrene. These differences are attributed to the particular magnitudes of the strength of the phase coupling between the matrix and the dispersed phase, which is controlled by their compatibility.

Additional Material: 7 Ill.