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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nuclear medicine 18 (1991), S. 791-795 
    ISSN: 1619-7089
    Keywords: Human thyroid ; Iodine 125 autoradiography ; In vitro labelling of thyroid tissue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Samples of fresh thyroid tissue obtained from 15 patients undergoing thyroid surgery were incubated with iodine 125 in culture solution to which thyroid-stimulating hormone (TSH) had been added and then examined by autoradiography. The radioactivity registered actively during the 90-min incubation period was primarily found in the lumina of follicles. Even morphologically similar follicles showed very heterogeneous uptake of radioiodine; small follicles often contained the highest concentrations of activity. The method applied appears to be particularly useful for answering the question as to whether and to what extent individual papillary or follicular thyroid carcinomas are able to store radioiodine. This information obtained immediately after surgery may contribute towards establishing the patient's prognosis and help in deciding on postoperative therapy and follow-up. Because of the heterogeneity of radioiodine uptake, it is mandatory to examine a representative sample of carcinoma tissue in order to obtain well-established results.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Neurosurgical review 12 (1989), S. 133-140 
    ISSN: 1437-2320
    Keywords: Brain edema ; brain swelling ; CT-densitometry ; head injury ; hyperaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two-hundred and fifty-two computerized tomography (CT) scans of 107 patients with head injuries were analyzed. The most frequent consequence of trauma was a diffuse swelling of the brain in 91% of the cases. The severity of brain swelling and its course can be estimated by the compression of (or absence of) the intracranial cerebrospinal fluid space. These observations may be of prognostic value as well. By measurement of theHounsfield units (HU) in 52 cases the blood or water content in the brain tissues was assessed. An increase in blood content of the tissues (hyperaemia) can account for an increase in Hounsfield values. A decrease in HU suggests brain edema. The density measurements showed that in the first hours and days following head injury, the diffuse brain swelling was caused by severe cerebrovascular congestion in the majority (53%) of the cases. Immediate brain edema without a preceeding hyperaemic phase occurs less frequently (32%). Between the 1st and 4th day after injury, edema started to prevail, and between the 5th and 8th day the edematous type of brain swelling was present almost exclusively.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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