ISSN:
1432-1076
Keywords:
C7 deficiency
;
haematuria
;
Chronic glomerulonephritis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A 14-year-old boy had persistent haematuria along with complete C7 deficiency. No significant changes in glomeruli and tubules were found in a renal biopsy specimen by light microscopy and immunofluorescence gave negative results for immune deposits. Electron microscopic examination demonstrated an attenuation of the glomerular capillary basement membrane without lamination and a diagnosis of thin basement membrane disease was made. It would be difficult to conclude that patients with C7 deficiency were predisposed to develop glomerulonephritis caused by immunologic aberrations. A family study failed to provide evidence of an association of C7 deficiency and thin basement membrane disease.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00441978
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