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  • 1
    Electronic Resource
    Electronic Resource
    Herpes simplex virus and oral mucositis in children with cancer (1994)
    Springer
    Supportive care in cancer 2 (1994), S. 266-269 
    Details
    ISSN: 1433-7339
    Keywords: HSV ; Stomatitis ; Cancer ; Pediatrics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The relationship between herpes simplex virus (HSV) and oral mucositis was investigated in children undergoing antineoplastic chemotherapy. HSV culture was performed in 20 children with stomatitis developing after antineoplastic chemotherapy. Viral isolates were typed and susceptibility to acyclovir was investigated. The virus was isolated from oral lesions in 10 of 20 children with severe oral mucositis. Viral reactivation was the most likely explanation in most cases, since HSV was isolated in 9 of 13 seropositive patients (and in 1 patient with unknown anti-HSV serology), but in no seronegative patient. HSV type 1 was isolated more frequently than HSV type 2 (8 versus 2). Acyclovir showed standard in vitro activity against all isolates. Our results suggest that oral mucositis in children receiving antineoplastic treatment is probably multifactorial in origin and that HSV can be an important cofactor, especially in children who are seropositive for HSV. In our Centre, acyclovir remains active in vitro against this opportunistic pathogen and could be employed in prophylaxis and therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00365734
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Zur Gaschromatographie kleinster Substanzmengen (Mikrogrammbereich) (1958)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 70 (1958), S. 310-311 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Es wird eine Auswertungsweise beschrieben, durch deren Hilfe man auf eine vollständige Trennung der Substanzen verzichten und den Zeit- und Materialbedarf wesentlich verringern kann.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19580701006
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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