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Tumor therapy and track structure (1999)

Kraft, G. ; Scholz, M. ; Bechthold, U.

Springer

Radiation and environmental biophysics 38 (1999), S. 229-237

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ISSN: 1432-2099

Keywords: Key words Ions ; Tumor therapy ; RBE ; Track structure ; Treatment planning ; Carbon beam

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Physics

Notes: Abstract The elevated relative biological effectiveness (RBE) of heavy ions like carbon is the main reason for their use in radiotherapy and is due to the microscopic distribution of dose inside each particle track. High local doses produce lesions that are expected to have a diminished possibility of repair. Thus, RBE depends on track structure and on the biological repair capacity of the tissue that is affected by the irradiation. For tumor treatment planning with heavy ions, the beam quality and the tissue sensitivity have to be taken into account. Using the dependence of radial dose distribution on particle energy and atomic number on the physical side and x-ray dose response for the repair capacity on the biological side, the response to particle irradiation can be calculated in the local effect model (LEM) and used for treatment planning. This article traces the route from electron emission as the basis of track structure to the RBE calculation and the application in treatment planning.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/s004110050163

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Polarographische Erfassung von auf DC-Plastikfolien getrennten Substanzen (1976)

OelschlÄger, H. ; Lumbantoruan, S. ; Volke, J. ; [et al.]

Springer

Fresenius' Zeitschrift für analytische Chemie 279 (1976), S. 257-261

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ISSN: 1618-2650

Keywords: Chromatographie, Dünnschicht/Polarographie ; Erfassung von auf Plastikfolien getrennten Substanzen

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology

Description / Table of Contents: Zusammenfassung Auf DC-Plastikfolien getrennte Substanzen lassen sich mit guter Genauigkeit (Wiederfindungsraten 〉 95 %) in Gegenwart des Folienmaterials gleichspannungspolarographisch durch Reduktion an der Hg-Tropfelektrode bestimmen. Die von den Leuchtpigmenten abgegebenen Zn-Ionen müssen vor der Registrierung der i-E-Kurven durch ÄDTA maskiert werden.

Notes: Abstract Organic compounds with polarographically active groups can be determined after separation by thin-layer chromatography on flexible polyester film by means of dc polarography in the presence of the foil. Heavy metal cations, such as Zn2+, derived from the fluorescent material of the stationary phase must be masked by complex formation with EDTA before the current-voltage curve is recorded. Recovery is 〉 95%.