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  • Cell & Developmental Biology  (2)
  • Endogenous depression  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Increased serum glutamate in depressed patients (1982)
    Springer
    European archives of psychiatry and clinical neuroscience 232 (1982), S. 299-304 
    Details
    ISSN: 1433-8491
    Keywords: Serum glutamate ; Endogenous depression ; Neurotic depression ; Antidepressants ; Serum-Glutamat ; endogene Depression ; neurotische Depression ; Antidepressiva
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der Serum-Glutamatgehalt wurde bei endogen depressiven, neurotisch depressiven, schizophrenen und schizoaffektiven Patienten sowie gesunden Kontrollpersonen bestimmt. Hierbei zeigte sich, daß die Serumglutamatspiegel bei endogen und neurotisch Depressiven signifikant höher waren als bei den anderen Gruppen. Zwischen schizophrenen und schizoaffektiven Patienten sowie Kontrollen zeigten sich dagegen keine signifikanten Unterschiede. Die weitere Analyse der Daten erbrachte die Hypothese, daß die erhöhten Serum-Glutamat-Konzentrationen bei endogen und neurotisch Depressiven eine Folge der antidepressiven Medikation sind. Diese Ergebnisse werden im Hinblick auf die Wirkung der Antidepressiva auf das Serum-Glutamat bei affektiven Störungen diskutiert.
    Notes: Summary Glutamate concentration was determined in serum from endogenous and neurotic depressive patients, in persons with schizophrenia or schizoaffective disorder, and in normal subjects. The mean serum glutamate level in the endogenous and neurotic depressive patients was found to be significantly higher than in any of the other groups. No other statistically significant differences were found. Statistical analysis revealed that the elevated serum glutamate concentration in the endogenous and neurotic depressive patients was probably caused by medication. These results are discussed in view of the effect of antidepressants upon the serum glutamate in the affective disorders.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00345492
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  • 2
    Electronic Resource
    Electronic Resource
    Levels of total and free tryptophan in the plasma of endogenous and neurotic depressives (1981)
    Springer
    European archives of psychiatry and clinical neuroscience 231 (1981), S. 35-39 
    Details
    ISSN: 1433-8491
    Keywords: Total tryptophan ; Free tryptophan ; Endogenous depression ; Neurotic depression ; Gesamt- und freies Tryptophan ; Endogene Depression ; Neurotische Depression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Gesamt- und freies Tryptophan wurde im Plasma von 34 endogen Depressiven, 20 neurotisch Depressiven und 25 gesunden Kontrollpersonen bestimmt. Während beim Gesamttryptophan kein Unterschied zwischen den drei Gruppen festgestellt werden konnte, war das freie Tryptophan bei endogen Depressiven und neurotisch Depressiven signifikant erniedrigt. Zwischen endogen und neurotisch Depressiven fand sich kein Unterschied.
    Notes: Summary The levels of total and free tryptophan were determined in the plasma of 34 endogenous depressives, 20 neurotic depressives and 25 healthy volunteers. Whilst the levels of total tryptophan were not different in the three groups, the level of free tryptophan was reduced in both endogenous and neurotic depressives. No difference could be found between endogenous and neurotic depressives.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00342828
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    A transient rise in intracellular Ca2+ is a precursor reaction to the zona pellucida-induced acrosome reaction in mouse sperm and is blocked by the induced acrosome reaction inhibitor 3-quinuclidinyl benzilate (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Molecular Reproduction and Development 32 (1992), S. 41-50 
    Details
    ISSN: 1040-452X
    Keywords: Fluo-3 ; Intracellular Ca2+ transient ; QNB ; Population kinetics ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The acrosome reaction induced by the zona pellucida in mouse sperm has been shown to proceed in two stages experimentally distinguishable by the fluorescent probe chlortetracycline. Entry into the first stage of sperm bound to isolated, structurally intact zonae pellucidae is blocked by the compound 3-quinuclidinyl benzilate. In this study, we show, utilizing the fluorescent Ca2+ indicator fluo-3, that the first stage of the zona-induced acrosome reaction is characterized by an increase in intracellular Ca2+, followed by a decrease as the acrosome reaction proceeds. This calcium transient is completely suppressed by 3-quinuclidinyl benzilate. We conclude that the Ca2+ transient is induced by the zona pellucida and is required for the zona-induced acrosome reaction. Blockage of this sperm intracellular Ca2+ transient provides a mechanism for the inhibitory action of 3-quinuclidinyl benzilate on the zona-induced acrosome reaction in mouse sperm. © 1992 Wiley-Liss, Inc.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrd.1080320108
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  • 4
    Electronic Resource
    Electronic Resource
    Transmission electron microscopy studies of plasma-etched silicon nitride/silicon carbide composites (1987)
    New York, NY : Wiley-Blackwell
    Journal of Electron Microscopy Technique 7 (1987), S. 161-166 
    Details
    ISSN: 0741-0581
    Keywords: Selective plasma etch ; Ceramic composites ; Transmission electron microscopy ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Natural Sciences in General
    Notes: Transmission electron microscopy has been used to isolate and examine the intergranular glass phase in hot-pressed silicon nitride/silicon carbide composites. Previously there have been difficulties in locating a suitable region for studies of this nature because the interfering nitride and carbide grains inhibit isolation of the glass for examination. Radiofrequency plasma etching of thinned sections of 6 wt% Y2O3, 2 wt% A12O3 in Si3N4 containing 30 vol% of SiC proved to be fruitful in isolating the glass phase. A mixture of CF4 and O2 quantitatively remove the acicular nitride phase without any evidence of attack on either the glass or carbide. Composites containing ceria and magnesia as substitutes for yttria behave similarly. This indicates that glasses containing minor to major concentrations of elements forming stable fluorides inhibit the attack of fluoride ions on silica glasses containing these elements.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jemt.1060070303
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    Paper (German National Licenses)
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