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  • 1
    Electronic Resource
    Electronic Resource
    The development of the chick pituitary with special reference to the cellular differentiation of the pars buccalisPresented at the Fiftieth Meeting of the American Association of Anatomists, 1938. Anat. Rec., vol. 70 (Suppl. no. 3), p. 64. (1939)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 64 (1939), S. 483-517 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1050640306
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  • 2
    Electronic Resource
    Electronic Resource
    Quantitative analysis of intramembranous particles in the membranous system of rat liver cells at different stages of development and aging (1981)
    New York, NY : Wiley-Blackwell
    Journal of Morphology 170 (1981), S. 133-146 
    Details
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The density of intramembranous protein particles was studied by freeze-fracture. Particle density on the fracture faces of the plasmalemma and the rough endoplasmic reticulum (RER), as well as the outer and inner membranes of the nucleus and the mitochondria in rat hepatocytes were quantified. Comparison among different age groups sampled days postcoitum (dpc), days postpartum (dpp), and months postpartum (mpp) shows age-related changes in particle density in each membrane system. With the exception of the RER, particle densities increased after the 16th dpc, reached a maximum at birth, and then decreased with increasing age. Simultaneously, the number nuclear pores shows a positive correlation with the particle density of the nuclear membranes. The particle density on the membranes of the RER shows a maximum on the 16th dpc, and on the 6th dpp. Thereafter, the density of the RER decreases slightly. In all membrane systems, the density of the particles on the external fracture faces is more variable than the density of the particles on the protoplasmic fracture faces.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jmor.1051700202
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  • 3
    Electronic Resource
    Electronic Resource
    A simian virus 40-encoded protein of Mr 74,000 daltons is structurally related to the capsid proteins of the virus (1983)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 22 (1983), S. 197-207 
    Details
    ISSN: 0730-2312
    Keywords: SV40 ; structural proteins ; immunoprecipitation ; tryptic peptide analysis ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: We have demonstrated the synthesis of a 74,000-dalton protein (74K protein) in African green monkey kidney cells infected with simian virus (SV)40. The 74K protein was detected late during the lytic cycle. Its synthesis was inhibited by arabinosyl cytosine as was the synthesis of the capsid proteins. Monospecific antibodies raised against VP1 and VP3 precipitated the structural proteins and the 74K protein. The 74K protein was not found in purified virions. Tryptic peptide analysis demonstrated that the 74K protein shares methionine- and serine-containing peptides with VP1 and VP3 and thus is structurally related to the capsid proteins.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240220402
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  • 4
    Electronic Resource
    Electronic Resource
    Antibodies specific for the carboxy-terminal region of the major surface glycoprotein of simian rotavirus (SA11) and human rotavirus (Wa) (1986)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 30 (1986), S. 41-49 
    Details
    ISSN: 0730-2312
    Keywords: rotaviruses ; antipeptide serum ; ELISA ; immunoprecipitation ; cross-reactivity ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Antibodies specific for the major outer capsid protein (VP7) of the simian rotavirus SA11 were obtained by immunization of rabbits with a synthetic peptide, Ser-Ala-Ala-Phe-Tyr-Tyr-Arg-Val, corresponding to the eight carboxy-terminal amino acids of the viral protein predicted from the nucleotide sequence of the gene segment 9 of the SA11 genome. As the carboxy-terminal region of the VP7 of human rotavirus Wa has an identical sequence, cross-reactivity of the raised antibodies was observed with this strain.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240300106
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  • 5
    Electronic Resource
    Electronic Resource
    Cross-reactivity of antibodies against synthetic peptides (1982)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 19 (1982), S. 119-125 
    Details
    ISSN: 0730-2312
    Keywords: SV40 ; polyoma ; tumor antigens ; cellular proteins ; immunoprecipitation ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Antiserum against the synthetic peptide Lys-Arg-Ser-Arg-His-Phe, corresponding to the carboxy terminus of polyoma virus medium tumor antigen (medium T antigen), immunoprecipitates a protein of 36,000 daltons from polyoma virus-infected and uninfected cell extracts treated with the sulfhydryl group reagent N-ethyl-maleimide. This protein appears to share an antigenic determinant with medium T antigen that is normally buried inside the protein or covered up by another protein or cellular structure. The two-dimensional tryptic fingerprints of the 36K protein and of medium T antigen are apparently unrelated to each other. Antiserum against the octapeptide Ac-Met-Asp-Lys-Val-Leu-Asn-Arg-Tyr, including the amino-terminal heptapeptide sequence of the simian virus 40 (SV40) large tumor (T) and small T antigens, cross-reacts with polyoma virus large T antigen, which has an identical amino-terminal heptapeptide sequence except that Lys is replaced by Arg and Asn by Ser. The problem of cross-reactivities of antipeptide sera is discussed.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240190203
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  • 6
    Electronic Resource
    Electronic Resource
    Antipeptide antibodies directed against the carboxy-terminal region of SV40 structural proteins VP2 and VP3 (1986)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 31 (1986), S. 277-287 
    Details
    ISSN: 0730-2312
    Keywords: Western blot ; ELISA ; competition ; immunofluorescence ; immune electron microscopy ; subcellular fractionation ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Rabbits were immunized with a synthetic heptapeptide of the sequence Arg-Asn-Arg-Ser-Ser-Arg-Ser corresponding to the carboxy-terminal region of the SV40 viral proteins VP2 and VP3. The raised antibodies recognize the viral proteins in enzyme-linked immunosorbent (ELISA) and Western blot assay. Specificity of the antibodies were confirmed by competition experiments. The antibodies recognize VP2 and VP3 in infected cells by immunofluorescence and in subcellular fractions by ELISA. No interaction with virions was observed.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcb.240310405
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  • 7
    Electronic Resource
    Electronic Resource
    Prerequisites for a photoreceptor structure in the crayfish tail ganglion (1963)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 209-217 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: On grounds of electron microscopic appearance (Hama, '60), the side of abdominal photoreceptor organ in crayfish (Orconectes virilis [Hagen]) has been questioned. Illumination of any part of ventral nerve cord (exclusive of A6 ganglion), e.g., A2, A3, A4, A5, and afferent roots of A6, shows no physiological response. A6 alone shows phototransduction process pulses. Sectioning of cord restricts locus to A6. Spurious effects from cephalic eye response were seen.Physiological investigation has restricted the crayfish-tail photoreceptor-organ to include photosensitive elements lying only within the sixth abdominal ganglion, and two to four B-fibers carrying nerve impulse responses through the ventral nerve cord. It is therefore possible to exclude the “Hama-structures,” associated with the giant fiber system, and located diffusely in the nerve cord, from any role in the phototransduction process. Attention of anatomists is called to this primitive and interesting photoreceptor organ.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091470205
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  • 8
    Electronic Resource
    Electronic Resource
    Contributions to an analysis of the avian vitelline membrane's potential to promote outgrowth of the yolk sac-serosal membrane (1976)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 184 (1976), S. 227-231 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Explanted blastoderms of freshly laid chicken eggs expand their area during the first 44-45 hours of incubation by a factor of at least 11 if they are placed with the epiblast on the inner surface of explanted fresh chick vitelline membrane and provided with chick egg extract. This expansion is due essentially to the spreading of the yolk sac-serosal membrane. On turkey and duck membrane the expansion factor is about 6 and 3.8 respectively under otherwise identical conditions, but 1.9 only on a semisolid nutrient agar plate. Only the inner surface of the vitelline membrane has this growth-promoting potential, which markedly and progressively declines during incubation in ovo because of systemic factors rather than because of a direct influence by the outgrowing yolk sac-serosal membrane. Trypsinization of fresh chick vitelline membrane (1% trypsin 3 hours) reduces the growth-promoting potential to about 40% of its normal strength. The outgrowth of the extraembryonic tissues on vitelline membrane is better supported in the presence of a species' own egg extract than by extract from another species.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091840208
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  • 9
    Electronic Resource
    Electronic Resource
    Development of the high endothelial venule in rat lymph node autografts (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 238 (1994), S. 473-479 
    Details
    ISSN: 0003-276X
    Keywords: High endothelial venules ; Autograph ; Lymph node ; RAF ; Regeneration ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Vascular reconstruction during rat lymph node regeneration was investigated in autotransplanted mesenteric lymph node fragments, which had been implanted in the renal parenchyma. In addition to light microscopy, vascular casting and transmission electron microscopy were used. From day 3 onwards capillaries grew into the autografts together with lymphatic vessels. The capillaries showed obvious signs of proliferation by day 5. The surviving interstitial cell at the outer border of the transplant produced extracellular substance. High endothelial venules (HEV) differentiated from capillaries from about day 7. A first sign of their development was a vessel with a narrow, branching luminal space and with endothelial cells containing rich cytoplasm and small Golgi complexes. As the Golgi complexes grew and the cisternae and vesicles increased, the lumen dilated, the cell coat on the luminal surface became prominent, and, finally, lymphocytes emigrated through these venules from around day 10. The typical lymph node structure was complete by day 28. These results suggest that the interaction among the remaining interstitial cells, invading capilaries, and lymphatic penetration results in differentiation and maturation of HEV in lymph node regeneration. The development of Golgi complexes is strongly associated with lymphocyte emigration from the blood. © 1994 Wiley-Liss, Inc.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1092380406
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  • 10
    Electronic Resource
    Electronic Resource
    Embryological development of the arterial system of the forelimb in Tupaia (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 240 (1994), S. 416-422 
    Details
    ISSN: 0003-276X
    Keywords: Tupaia ; Forelimb ; Artery ; Comparative embryology ; Three-dimensional reconstruction ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Background: The arterial system of the upper extremities in man shows drastic developmental changes and many individual variations related to interspecific variations in primates. The ontogenetic development in Tupaia was examined from the viewpoint of comparative embryology.Methods: Histological specimens of 39 embryos were observed and reconstructed in three dimensions using a computer program. Four adult animals were dissected and examined with angiography to ascertain the end stage of development.Results: At the proximal end of the upper arm the deep brachial artery appears first as a concomitant vessel with the radial nerve. It becomes reduced in size and is succeeded by the posterior circumflex humeral artery, which is accompanied initially by the axillary nerve and finally by the radial nerve. The main arterial passageway to the fingers consists of the brachial and interosseous arteries during early development. The superficial brachial artery and median artery are formed later, and their connection becomes the main route of blood supply for the finger arteries up to the adult stage. The ulnar artery is formed at the end of arterial development to form the ulnar end of the superficial palmar arch. The superficial antebrachial arteries are also recognized.Conclusions: All the arterial elements of the forelimb in Tupaia are observed in a variety of primates, including man, and the characteristics of Tupaia are thought to represent the primitive conditions of the common ancestor of tree shrews and primates. © 1994 Wiley-Liss, Inc.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1092400314
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