ISSN:
0749-1581
Keywords:
β-Lactam antibiotics
;
Penicillin
;
Cephalosporin
;
13C NMR
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The 13C NMR features of most β-lactam antibiotics of the penicillin and cephalosporin groups in clinical use are presented and reviewed. Data on precursor and breakdown products are included in the survey, with particular reference to benzylpenicillin. Penicillin and cephalosporin spectra are discussed, and points of similarity and difference emphasized. The potential of the data for solving problems of analysis, stability, degradation and biological structure-activity relationships is summarized.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260240602
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