ISSN:
0749-1581
Schlagwort(e):
β-Lactam antibiotics
;
Penicillin
;
Cephalosporin
;
13C NMR
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
The 13C NMR features of most β-lactam antibiotics of the penicillin and cephalosporin groups in clinical use are presented and reviewed. Data on precursor and breakdown products are included in the survey, with particular reference to benzylpenicillin. Penicillin and cephalosporin spectra are discussed, and points of similarity and difference emphasized. The potential of the data for solving problems of analysis, stability, degradation and biological structure-activity relationships is summarized.
Zusätzliches Material:
4 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/mrc.1260240602