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Solid state fermentation for cephalosporin production byStreptomyces clavuligerus andCephalosporium acremonium (1989)

Jermini, M. F. G. ; Demain, A. L.

Springer

Cellular and molecular life sciences 45 (1989), S. 1061-1065

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ISSN: 1420-9071

Keywords: Solid state fermentation ; β-lactam antibiotics ; cephalosporins ; Streptomyces clavuligerus ; Cephalosporium acremonium

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary Solid state fermentation systems were developed for the production of cephalosporins withStreptomyces clavuligerus andCephalosporium acremonium. S. clavuligerus NRRL 3585 was grown on moistened barley under optimum solid state fermentation conditions for 7 days; approximately 300 μg cephalosporins per g substrate were extracted from the kernels.C. acremonium C-10 produced approximately 950 μg cephalosporin C per g substrate after 10 days of solid state fermentation.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01950159

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