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  • 1
    Electronic Resource
    Electronic Resource
    Cerebellar feedback signals of a passive hand movement in the awake monkey (1984)
    Springer
    Pflügers Archiv 402 (1984), S. 292-299 
    Details
    ISSN: 1432-2013
    Keywords: Cerebellum ; Climbing fibre ; Purkinje cell ; Awake monkey ; Passive movement ; Sensory feedback
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract From three intact and awake monkeys, 149 Purkinje cells and 44 presumed mossy fibres were recorded in the intermediate part of the cerebellar anterior lobe, and this activity was analyzed with regard to different parameters of a passive hand movement. The tonic discharge rate of the simple spikes (SS) varied according to different joint positions only in a single Purkinje cell, whereas such a position relation was found in nine out of 44 presumed mossy fibres. A phasic increase of the complex spike (CS) discharge rate of Purkinje cells in response to passive wrist movements usually occurred within 100 ms after movement onset. However, in some units a phase of increased CS rate was observed which lasted for the whole movement duration. The amount of this phasic increase in the CS rate depended on the acceleration of movement, but the SS response to movements of different velocity remained unchanged.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00585512
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The role of the cortical parts of the cerebellar hemispheres in discrimination learning of cats (1970)
    Springer
    Pflügers Archiv 318 (1970), S. 346-352 
    Details
    ISSN: 1432-2013
    Keywords: Cerebellärer Cortex ; Instrumentelle Konditionierung ; Licht-Dunkelheit-Diskrimination ; Cerebellar Cortex ; Instrumental Conditioning ; Light-Dark-Discrimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Eighteen cats were used as subjects in a study which investigated the effects of bilateral cortical cerebellar hemispheric ablations upon light-dark discrimination learning. From the operated control group (8 animals), 5 were tested two weeks and 3 three weeks postoperatively. From the experimental group (10 animals) 4 were tested two weeks and 6 three weeks postoperatively. The discrimination task consisted of an instrumentally conditioned bar-pressing response. The results showed that almost during the entire 23-day learning period, the experimental cats performed more poorly on the discrimination task than their controls. It is hypothesized that the difference between the two groups of animals derives from the disturbance (caused by the ablation) of the connections between the cerebellum and other structures involved in the habituation process.
    Notes: Zusammenfassung 18 Katzen wurden als Versuchstiere in einem Experiment benutzt, welches den Einfluß der bilateralen Entfernung des corticalen Teils der cerebellären Hemisphären auf das Erlernen einer Licht-Dunkelheit-Diskrimination untersuchte. Von der operierten Kontrollgruppe (8 Tiere) wurden 5 zwei Wochen und 3 drei Wochen nach der Operation getestet. Von der experimentellen Gruppe (10 Tiere) wurden 4 zwei Wochen und 6 drei Wochen nach der Operation getestet. Die Diskriminationsaufgabe bestand aus Hebeldrücken nach der Skinner-Methode. Die Ergebnisse zeigten, daß die experimentellen Tiere fast während der ganzen Lernperiode (23 Tage) weniger Diskriminationsvermögen aufweisen als die Kontrolltiere. Es wurde vermutet, daß dieser Unterschied zwischen den experimentellen Tieren und den Kontrolltieren darauf beruht, daß die Entfernung eines Teils des cerebellären Cortex die Verbindungen zu Strukturen, die bei dem Habituationsprozeß eine Rolle spielen, stört.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00586974
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The effect of pentothal on the activity evoked in the cerebellar cortex (1973)
    Springer
    Experimental brain research 17 (1973), S. 50-62 
    Details
    ISSN: 1432-1106
    Keywords: Cerebellum ; Barbiturates ; Unitary activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In precollicular decerebrate cats, limb nerves have been stimulated and field potentials and unitary activity recorded from the cerebellar cortex. Doses of pentothal up to 8 mg/kg affect neither the activity evoked in the fast mossy fibre pathways, nor the size of the postsynaptic potentials in granule cells, but the axon discharge in these latter cells is clearly affected. With 4–8 mg/kg the axon discharge of granule cells is abolished and as a consequence Purkinje cells do not respond to the peripheral stimulation via the mossy fibres. In contrast the activity evoked through the climbing fibres is enhanced. This effect takes place at precerebellar level. Both the effects on the mossy fibre and climbing fibre pathways show a recovery in 15–60 min depending on the dose.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234563
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The effects of unilateral and bilateral cortical ablations of the cerebellar hemisphere upon learning and retention of an instrumental light-dark discrimination task in adult cats (1969)
    Springer
    Pflügers Archiv 310 (1969), S. 101-108 
    Details
    ISSN: 1432-2013
    Keywords: Cerebellärer Kortex ; Lernen am Erfolg ; Licht-Dunkelheit-Diskrimination ; Cerebellum ; Instrumental Conditioning ; Light-Dark Discrimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Ten adult cats were used as subjects in a study which was designed to investigate the effects of cortical ablations of the cerebellar hemispheres upon learning and retention of a light-dark discrimination task. The discrimination task was instrumentally conditioned in food-deprived cats. The results of this study showed that unilateral or bilateral ablations of the cerebellar hemispheres have no effects upon retention of a learned discrimination task. The data further indicated that bilateral ablations of the cerebellar hemispheres seem to retard learning of a discrimination task during the first 5 days of the learning period. This latter effect was interpreted to be due to a dynamic period of compensation, during which, asCarrea andMettler [3] assumed, the cerebral cortex takes over the functions of the ablated parts of the cerebellum.
    Notes: Zusammenfassung Zehn Katzen wurden als Versuchstiere in einem Experiment benutzt, welches die Einflüsse der Entfernung der corticalen cerebellären Hemisphären auf das Erlernen und Behalten einer Licht-Dunkelheit Diskrimination untersuchte. Die Diskriminationsaufgabe wurde bei hungrigen Katzen nach der Skinner Methode durchgeführt. Die Ergebnisse dieser Studie zeigten, daß unilaterale oder bilaterale Entfernungen der cerebellären corticalen Hemisphären keinen Einfluß auf das Behalten der erlernten Diskriminationsaufgabe hatten. Dagegen schien die bilaterale Entfernung der cerebellären corticalen Hemisphären das Erlernen der Diskriminationsaufgabe zu verzögern, besonders während der ersten 5 Tage der Lernperiode. Es wurde angenommen, daß dieser einfluß auf einer dynamischen Kompensationsperiode beruht, während der, wieCarrea undMettler [3] vermuteten, der cerebrale Kortex die Funktion der entfernten Teile des Kleinhirns übernimmt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00586767
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    Paper (German National Licenses)
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