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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 17 (1973), S. 50-62 
    ISSN: 1432-1106
    Keywords: Cerebellum ; Barbiturates ; Unitary activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In precollicular decerebrate cats, limb nerves have been stimulated and field potentials and unitary activity recorded from the cerebellar cortex. Doses of pentothal up to 8 mg/kg affect neither the activity evoked in the fast mossy fibre pathways, nor the size of the postsynaptic potentials in granule cells, but the axon discharge in these latter cells is clearly affected. With 4–8 mg/kg the axon discharge of granule cells is abolished and as a consequence Purkinje cells do not respond to the peripheral stimulation via the mossy fibres. In contrast the activity evoked through the climbing fibres is enhanced. This effect takes place at precerebellar level. Both the effects on the mossy fibre and climbing fibre pathways show a recovery in 15–60 min depending on the dose.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2013
    Keywords: Cerebellärer Kortex ; Lernen am Erfolg ; Licht-Dunkelheit-Diskrimination ; Cerebellum ; Instrumental Conditioning ; Light-Dark Discrimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Ten adult cats were used as subjects in a study which was designed to investigate the effects of cortical ablations of the cerebellar hemispheres upon learning and retention of a light-dark discrimination task. The discrimination task was instrumentally conditioned in food-deprived cats. The results of this study showed that unilateral or bilateral ablations of the cerebellar hemispheres have no effects upon retention of a learned discrimination task. The data further indicated that bilateral ablations of the cerebellar hemispheres seem to retard learning of a discrimination task during the first 5 days of the learning period. This latter effect was interpreted to be due to a dynamic period of compensation, during which, asCarrea andMettler [3] assumed, the cerebral cortex takes over the functions of the ablated parts of the cerebellum.
    Notes: Zusammenfassung Zehn Katzen wurden als Versuchstiere in einem Experiment benutzt, welches die Einflüsse der Entfernung der corticalen cerebellären Hemisphären auf das Erlernen und Behalten einer Licht-Dunkelheit Diskrimination untersuchte. Die Diskriminationsaufgabe wurde bei hungrigen Katzen nach der Skinner Methode durchgeführt. Die Ergebnisse dieser Studie zeigten, daß unilaterale oder bilaterale Entfernungen der cerebellären corticalen Hemisphären keinen Einfluß auf das Behalten der erlernten Diskriminationsaufgabe hatten. Dagegen schien die bilaterale Entfernung der cerebellären corticalen Hemisphären das Erlernen der Diskriminationsaufgabe zu verzögern, besonders während der ersten 5 Tage der Lernperiode. Es wurde angenommen, daß dieser einfluß auf einer dynamischen Kompensationsperiode beruht, während der, wieCarrea undMettler [3] vermuteten, der cerebrale Kortex die Funktion der entfernten Teile des Kleinhirns übernimmt.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 402 (1984), S. 292-299 
    ISSN: 1432-2013
    Keywords: Cerebellum ; Climbing fibre ; Purkinje cell ; Awake monkey ; Passive movement ; Sensory feedback
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract From three intact and awake monkeys, 149 Purkinje cells and 44 presumed mossy fibres were recorded in the intermediate part of the cerebellar anterior lobe, and this activity was analyzed with regard to different parameters of a passive hand movement. The tonic discharge rate of the simple spikes (SS) varied according to different joint positions only in a single Purkinje cell, whereas such a position relation was found in nine out of 44 presumed mossy fibres. A phasic increase of the complex spike (CS) discharge rate of Purkinje cells in response to passive wrist movements usually occurred within 100 ms after movement onset. However, in some units a phase of increased CS rate was observed which lasted for the whole movement duration. The amount of this phasic increase in the CS rate depended on the acceleration of movement, but the SS response to movements of different velocity remained unchanged.
    Type of Medium: Electronic Resource
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