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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Molecular Reproduction and Development 29 (1991), S. 238-244 
    ISSN: 1040-452X
    Keywords: IGF-IA ; Long 3′-end ; Expression ; Transcripts sizes ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: A cDNA clone of 525 bp corresponding to the 3′-untranslated region of insulin-like growth factor-I was isolated from a human placenta library. The sequence of this clone extended 200 nucleotides downstream from the previously reported 3′-end of IGF-IA cDNA, indicating the existence of IGF-IA transcripts having an even larger 3′-untranslated region. By using this clone for RNA transfer blot hybridization, it was shown that this longer 3′-untranslated region is included in the 7.5- and 5.0-kb transcripts, but not in the 1.1- and 0.9-kb transcripts. It is also apparent that transcripts bearing the extended 3′-untranslated sequence are highly expressed in human placenta.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 23 (1983), S. 530-533 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: In this study characteristics of polynorbornene (PNR) and ethylene-propylene terpolymer (EPDM) blends were examined in terms of compatibility, cocuring, and ozone resistance. For most of the blend compositions, two glass transition temperatures (Tg) at about -30 and -50°C were observed from differential scanning calorimetry data for both uncured and cured samples. The transitions correspond to the Tg's of the component polymers, suggesting that the blends are microheterogeneous. The two-phase blends are difficult to cocure as evidenced by the fact that tensile strengths of the blends, when plotted as a function of blend composition, deviate from the linear or additive behavior. Improved cocuring of the blends, however, can be achieved by matching the cure rates of the components. The ozone resistance of the blends containing 25 percent or more EPDM was substantially improved as compared with that of PNR. Therefore, the newly developed PNR can be used for applications requiring ozone resistance by properly blending it with EPDM.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 40 (1994), S. 419-423 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Three-dimensional Stokes flow through a thin screen which has a regular array of holes with two orthogonal axes of symmetry has been studied. The governing equation is simplified by the Roscoe potential and solved by an efficient eigenfunction expansion and collocation method. The resistance is found for circular and square holes in square arrays, and circular and hexagonal holes in triangular arrays.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 40 (1994), S. 407-418 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A population-balance-equation model is employed for the analysis of liquid-liquid extraction columns. This model considers drop breakage, coalescence, and exit phenomena for the drop phase caused by drop-drop and drop-continuous phase interactions. Drop breakage and coalescence rates are employed from a previous study on liquid dispersions in stirred-tank contactors. A drop exit frequency is developed based on a stochastic modeling approach. The model is tested by drop size distribution and dispersed-phase volume fraction (holdup) data obtained for a multistage column contactor of pilot-plant scale. Steady-state drop size distribution and transient holdup measurements are obtained by a photomicrographic technique and an ultrasonic technique, respectively. The model can predict flooding of the column. The effect of mass transfer on the hydrodynamic parameters of the contactor is also examined. The population-balance-equation model can be used for the control of extraction columns and can be extended to include mass-transfer calculations for the prediction of extraction efficiency.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 27 (1981), S. 207-212 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A viscous lamina of given mean thickness flows down a wavy incline. Assuming low Reynolds number and small perturbations due to the wavy striations, the velocity profiles and the free surface profile are determined. It is found that the amplitude and phase shift of the free surface depend, in a complicated manner, on the surface tension and the wave length and orientation of the wavy striations. The motion of a particle on the free surface experiences drift which is also a function of the surface tension, the amplitude, wave length and orientation of the wavy incline.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 26 (1980), S. 680-683 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 32 (1986), S. 667-676 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The relative influence of dispersed-phase viscosity and interfacial tension on equilibrium drop size and drop size distribution is studied for dilute suspensions by dispersing various silicone oils in water, methanol, and their solutions. Correlations for Sauter mean diameter, D32, are developed in terms of system variables using the mechanistic models of Part I. Drop sizes for low to moderate viscosity dispersed phases are normally distributed in volume and can be correlated by normalization with D32. Trends in the distributions are explained in terms of a parameter representing the relative resistance to breakage.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 28 (1982), S. 1016-1019 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The steady diffusion across a constant thickness corrugated barrier is analyzed through the intrinsic coordinate system. Perturbation solutions are found when the thickness is small compared to the minimum radius of curvature. For a given perimeter length, diffusive transfer is decreased, while for given maximum geometric dimensions, diffusive transfer may be increased by corrugations.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 193 (1992), S. 152-163 
    ISSN: 0002-9106
    Keywords: Cerebral endothelium ; Development ; Immunocytochemistry ; Rat ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A constant supply of blood-borne glucose is vital to cerebral metabolism. Although transport of glucose into the nervous tissue, effectively separated from the blood by a functional barrier (the blood-brain barrier, BBB), is one of the essential properties of the cerebral endothelium, little is known about its metabolic regulation and developmental expression in the BBB. In this study we provide evidence by immunocytochemistry that the pattern of the brain endothelial glucose transporter in rat brains (BBB-GT), immunologically homologous with the human hepatoma (G2), human erythrocyte transporter (Glut 1), changes with BBB maturation. While the neuroepithelium at embryonic days 12 and 13 shows a high incidence of immuno-detectable BBB-GT, vascularisation of the cerebral anlage and subsequent development of vascular tightness, as evidenced by intravascularly applied horseradish peroxidase and fluorescinated dextrans, is accompanied by a significant reduction BBB-GT expression in neuroepithelial cells and confinement of BBB-GT expression to the cerebral endothelium. Immunoblots and Northern blots of embryonic brain homogenates corroborate this change in BBB-GT expression in the brain anlage at the time of BBB maturation. However, low molecular weight glucose transporters, presumed to be of non-endothelial origin, are less dramatically reduced. The development of BBB tightness, therefore, seems to play a pivotal role in the pattern of BBB-GT expression during brain differentiation.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 32 (1986), S. 677-681 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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