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  • 1
    Electronic Resource
    Electronic Resource
    Pharmacodynamic profile of CQP 201-403, a novel 8α-amino-ergoline (1988)
    Springer
    Cellular and molecular life sciences 44 (1988), S. 431-436 
    Details
    ISSN: 1420-9071
    Keywords: CQP 201-403 ; 8α-amino-ergolines ; ergot pharmacology ; D-2 agonist ; endocrine ; CNS ; cardiovascular actions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The profile of action in animals of CQP 201-403, a novel 8α-amino-ergoline, is in most aspects that of a very potent dopaminomimetic, both as a prolactin secretion inhibitor, and at the levels of the CNS and the cardiovascular system. Qualitatively CQP 201-403 differs slightly from bromocriptine and apomorphine in its effects on the CNS (no influence on serotonin metabolism in the rat cortex; induction of masculine mounting behavior in rats) and the cardiovascular system of the dog (reflex tachycardia in response to a blood-pressure fall). In man the new compound proved to be highly active in lowering prolactin serum levels and to be more potent than bromocriptine (Parlodel®).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01940539
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Mass spectrometry of pyrrolo [2, 3- b] pyrazines and pyrazino [2, 3- b]indole (1977)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 12 (1977), S. 421-423 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The first mass spectra of pyrrolo [2, 3-b] pyrazine and some of its derivatives and of pyrazino [2, 3-b] indole are reported and compared with those of related compounds. Differences between the spectra of some aryl substituted derivatives are described and discussed.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210120703
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Bond polarizability calculations of the Raman optical activity of (R)-(+)-3-Methylcyclohexanone (1982)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 13 (1982), S. 155-159 
    Details
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The bond polarizability theory of Raman optical activity is used to calculate the complete Raman optical activity spectrum of (R)-(+)-3-methylcyclohexanone. The results are compared with the observed depolarized Raman circular intensity difference spectrum in the region 50-1800 cm-1. The predictions are better in the upper half of this range probably because at lower frequency the calculated normal coordinates are less reliable and the contributions from carbonyl deformations increase.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jrs.1250130211
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    Paper (German National Licenses)
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