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  • 1
    ISSN: 1432-1106
    Keywords: Optic axons ; Normal development ; Synaptic plasticity ; Goldfish
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Optic axons were cut in the goldfish optic nerve or tectum, filled with horseradish peroxidase and traced in tectal wholemounts. Many of them ran in conspicuous fascicles which curved across the tectum. Axons from central nasal retina, which ran in the most rostral fascicles, turned abruptly as they left these fascicles; ran caudally in a diffuse, parallel array for up to half the tectal length; and passed beneath more caudal fascicles to innervate the caudal half-tectum. Axons from peripheral nasal retina ran in the most caudal fascicles and terminated near their turning-points. Axons from temporal retina entered the tectum at its rostral margin and ran caudally from their points of entry to innervate the rostral halftectum. The resultant pattern was entirely consistent with the proposal that a slow caudal migration of optic terminals compensates during normal development for disparate modes of retinal and tectal growth.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 51 (1983), S. 433-442 
    ISSN: 1432-1106
    Keywords: Optic axons ; Regeneration ; Optictectum ; Retrograde tracing ; Goldfish
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To compare the distributions of normal and regenerated optic axons in the goldfish tectum, small groups of axons crossing the rostromedial tectum were cut and filled with horseradish peroxidase which subsequently revealed the retinal locations of their somata. In normal fish, the peroxidase-filled ganglion cells were virtually confined to a narrow arc spanning the ventronasal quadrant of the retina. In fish with regenerated visual projections (50–736 days after optic nerve transection, optic nerve crush or deflection of optic axons to the ipsilateral tectum) the filled cells were distributed across the full extent of the retina from centre to periphery and were less rigidly confined within appropriate quadrants. The absence of any detectable arc of filled cells in the ventronasal quadrant after regeneration showed that few, if any, of the regenerated axons followed their original paths across the tectum. Quantitative analysis of local cell distributions indicated that axons were re-routed independently rather than in groups. Nevertheless, axons consistently displayed a crude bias towards appropriate tectal regions, even in ipsilateral tecta where the relative positions of these regions are inverted. These results imply that regenerating optic axons are widely scattered by the effects of surgery. They may subsequently show preferences for appropriate central paths but with a resolution too low to define much more than the orientation of the retino-tectal map. Since there is both anatomical and electrophysiological evidence that regenerated optic terminal arborizations eventually adopt a precise retinotopic arrangement, this arrangement must chiefly reflect ordering mechanisms which act in the final stages of axon growth or synapsis.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 1 (1974), S. 358-362 
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A quantitative method for loading nanogram samples onto field desorption emitter wires is described. Sample consumption is reduced and problems with emitter wettability are overcome by freezing microliter droplets onto the emitters. Using this technique, good spectral data are obtained from 10 to 50 ng of material. Field desorption sensitivity measurements are reported for neomycin B, adenosine and cholesterol. Evaluation of the nonquantitative dipping technique previously employed reveals poor and nonreproducible sample loading efficiency.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 4 (1977), S. 284-290 
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Because of poor field ionization sensitivity or an insufficient number of peaks, conventional reference materials are inadequate for field desorption mass spectrometry. Hexakis (multifluoroalkoxy)cyclotriphosphazenes satisfy a growing need for high molecular weight reference compounds amenable to either electron impact or field ionization. In comparison with tris(perfluoroalkyl)-s-triazine standards, the substituted phosphazenes offer greater volatility, easier synthesis and better mass spetral characteristics. Phosphazene mixtures, in particular, cover a broad mass range in either ionization mode, creating new measurement capabilities for ions at high masses.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Isolation of a pentaene macrolide antibiotic (NSC-277813) from Streptomyces griseus (FCRC-21) fermentation broth is described. Using field desorption mass spectrometry and high resolution field desorption mass spectrometry on the intact and derivatized antibiotic and degradation products, the antibiotic was identified as fungichromin. The application of field desorption mass spectrometry in the identification of polyene antibiotics is discussed.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 69 (1936), S. A38 
    ISSN: 0365-9631
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science Part A: General Papers 3 (1965), S. 3511-3517 
    ISSN: 0449-2951
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: In attempts to homopolymerize benzaldehyde with various ionic and coordination catalysts, or by γ-radiation, only the ionic catalyst BF3 etherate formed a polymeric product. This product was identified as polybenzyl with a degree of polymerization (DP) of 133. Mixtures of benzaldehyde and styrene did not copolymerize under γ-irradiation, but yielded only polystyrene. With a BF3 etherate catalyst, however, mixtures of styrene and benzaldehyde were found to have copolymerized through the carbonyl group of the latter, and a 50 : 50 styrene-benzaldehyde monomer mixture yielded an 80:20 styrene-benzaldehyde copolymer with a DP of 139.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 64 (1931), S. 2936-2936 
    ISSN: 0365-9631
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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