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  • 1
    ISSN: 1432-1920
    Keywords: Chlorpromazine ; contrast media ; interaction ; neurotoxicity ; subarachnoid injection ; subdural injection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary During a 14-day period, 45 of 78 rabbits were treated intravenously with chlorpromazine (5 mg kg-1 day-1). Metrizamide or iohexol was injected subarachnoidally and the neurotoxic effects of each substance on rabbit behaviour were evaluated for 3 h in both chlorpromazine-treated and non-treated rabbits. Chlorpromazine increased both the excitative and the depressive effects of metrizamide and the depressive effects of iohexol. No signs of excitation were observed in chlorpromazine-treated and non-treated rabbits after subarachnoid injections of iohexol. In spite of a free flow of clear fluid from the needle both before and after the intended subarachnoid injection, radiography disclosed that 26 of 67 suboccipital injections inadvertently resulted in a subdural deposition of the contrast medium. Contrast medium effects following subdural injection significantly differed from those following subarachnoid injection.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 37 (1995), S. 471-474 
    ISSN: 1432-1920
    Keywords: Key words Paranasal sinuses ; Incidental finding ; Interval change ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Abnormal opacification of paranasal sinuses on brain MRI was studied in 178 consecutive adult patients who underwent two examinations separated by at least 4 months because of suspected neurological disease. Sinus abnormality was present in 79 (44 %) patients; in 60 % the abnormality involved two or more sinuses and it was bilateral in 51 %. The most frequently abnormal sinus was the maxillary (46 %), followed by the ethmoid (32 %), sphenoid (16 %), and frontal sinuses (6 %). Interval occurrence or complete resolution of abnormalities was observed in 52 % of patients (66 % of the sinuses). In the remaining 48 % of patients the abnormalities were present on two or more examinations, unchanged or of increased or decreased severity. The most frequent interval changing abnormalities were complete sinus opacification and fluid levels, followed by irregular mucoperiosteal thickening more than 4 mm thick. No polypoid abnormalities (polyps or mucosal cysts) decreased over time.
    Type of Medium: Electronic Resource
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