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  • Chromosome 16  (2)
  • Abnormal marrow eosinophils  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Acute eosinophilic leukemia: characterization by cytochemistry, chromosomal analysis, and in vitro colony formation (1985)
    Springer
    Journal of molecular medicine 63 (1985), S. 133-137 
    Details
    ISSN: 1432-1440
    Schlagwort(e): Eosinophilic leukemia ; Chromosome 16 ; Morphology ; Cytochemistry ; Colony-forming cells
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A pericentric inversion of chromosome 16 and acute myelomonocytic leukemia [AMMoL, M4 French-American-British (FAB)] with abnormal bone marrow eosinophils has recently been shown to form a new cytogenetic-clinicopathological entity. A patient otherwise undistinguishable from the more typical cases but lacking the FAB criteria for AMMoL is described. In such a situation, in vitro colony formation closely resembling that of acute myoblastic leukemia together with the clinical, morphological, cytochemical, and cytogenetic characteristics reported might serve as an indicator that these patients run an acute course justifying a diagnosis of acute eosinophilic leukemia and immediate institution of aggressive chemotherapy. The importance of the in vitro growth pattern regarding the differential diagnosis of disorders associated with predominant proliferation of eosinophils is discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01734251
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Acute myelomonocytic leukemia with involvement of eosinophils and inversion of chromosome 16 (1984)
    Springer
    Annals of hematology 48 (1984), S. 263-267 
    Details
    ISSN: 1432-0584
    Schlagwort(e): Leukemia, acute myelomonocytic ; Abnormal marrow eosinophils ; Chromosome 16
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A case of acute nonlymphocytic leukemia (ANLL) with abnormal marrow eosinophils is presented. Thorough morphological, cytochemical, and cytogenetic studies confirm the existence of a recently defined new cytogeneticmorphological entity: acute myelomonocytic leukemia with abnormal bone marrow eosinophils (FAB M4), chloracetate esterase- and periodic acid-Schiffpositivity of eosinophilic granules, and pericentric inversion of chromosome 16, in this case combined with trisomy 8. So far 18 such cases have been reported from a single institution. The implications of this new association on the diagnosis of acute leukemia with abnormal eosinophils are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00320396
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
    Volltext
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