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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Current genetics 4 (1981), S. 205-214 
    ISSN: 1432-0983
    Keywords: Cellcycle ; Gl period ; cdc genes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Here we report the isolation of several new temperature-sensitive mutations which cause cells of the yeast Saccharomyces cerevisiae to arrest in the G1 period of the cell cycle. Four different selection schemes were employed. The cell division cycle (cdc) mutations define five new complementation groups. At non-permissive temperatures, strains bearing these new cdc mutations arrested in G1 within one cell division cycle. By order-of-function mapping, cells of each population were found to be arrested at “start”, the regulatory point in the G1 period of yeast. Mutations were grouped into two categories by the abilities of mutant strains to continue extensive macromolecular synthesis and to conjugate with cells of the opposite mating type. For strains with mutations in one category, shift to the non-permissive temperature caused an abrupt decrease in the rates of labelling of protein and RNA, and rendered cells unable to mate efficiently. For strains with mutations in the second category, cells continued to grow and mating ability was not significantly impaired. Each selection scheme was also designed to isolate mutations which specifically affect the ability of cells to reinitiate the cell cycle from stationary phase. This was done to test the hypothesis that stationary phase cells are in a unique developmental state referred to as G0. No mutations specific for resumption of growth from stationary phase were isolated.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 39 (1977), S. 1-26 
    ISSN: 1432-1246
    Keywords: Health status ; Stress ; Job-satisfaction ; Rank of importance ; Cluster analysis. ; Gesundheitsstatus ; Belastungsempfinden ; Arbeitszufriedenheit ; Bedeutungsrangfolge ; Clusteranalyse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Eine Vollerhebung der sozialpsychologischen Situation von Fluglotsen (N = 517) mit nominalstatistischen Daten wurde clusteranalytisch ausgewertet. Das Ergebnis der multivariaten Analyse wurde unter methodischen und inhaltlichen Aspekten mit univariaten Auswertungen von Singer und Rutenfranz (1972) verglichen: Cluster zur personalen Umgebung spezifizieren Aussagen zum typischen Lotsen. Mittlere Bedeutungsrangfolgen zu Variablen der Arbeitssituation werden in Gruppen gegenteiliger Meinung aufgelöst und in Beziehung zur Arbeitszufriedenheit gebracht. Gruppen von Lotsen mit guter Zufriedenheit werden von stark unzufriedenen separiert. Aussagen zur negativen Einschätzung des gesamten Berufsweges werden durch Cluster belegt, besondere Probleme einzelner Dienstorte herausgefiltert. Die Gesamtheit der Lotsen wurde nach subjektivem Gesundheitsstatus mit Krankheitssymptomen und therapeutischen Maßnahmen gegliedert. Beziehungen zwischen Gesund-heitsstörungen, Arbeitsunzufriedenheit, Belastung und Bedeutungsgewichtung von Aspekten der Arbeitssituation werden aufgezeigt und teilweise durch Motivations-und Zufriedenheitstheorien erklärt.
    Notes: Summary A total inventory about the sociopsychological situation of german air-traffic controllers (N = 517) with data on nominal scales was analysed by cluster analysis. The results of the multivariate analysis were compared with those of univariate analysis by Singer and Rutenfranz (1972) in methodology and substance: Clusters concerning the family situation specify statements to the “typical controller”. Mean rankings of importance of variables of the work-situation are split into groups of contradictory meanings and are related to job satisfaction. Groups of controllers with good job satisfaction are separated from the dissatisfied. Negative estimations of the career are substantiated by clusters. Special problems of some airports are filtered out. The collectif of all air traffic controllers is structured according to subjective health status, symptoms of illness and therapeutics. Relations between health disturbances and job satisfaction, stress and rankings of importance of aspects of work situation are pointed out and partially explained with motivation- and job-satisfaction theories.
    Type of Medium: Electronic Resource
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