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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 286 (1994), S. 35-40 
    ISSN: 1432-069X
    Keywords: Epidermolysis bullosa acquisita ; Colchicine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The treatment of epidermolysis bullosa acquisita (EBA) is difficult and often disappointing. We report on the successful treatment of two EBA patients with colchicine. The drug was administered orally at an initial dose of 2 mg/day. After 2 weeks of therapy a dramatic improvement was observed. Most of the cutaneous and buccal mucosal lesions had healed and both of the patients were able to go about their normal daily activities. In the first patient the disease was refractory to dapsone alone or combined with steroids. In the second patient no other treatment was tried. After 6 months a maintenance dose of 1 mg/day colchicine was given. The disease had remained stable in both patients at the time of writing for more than 8 months. No side effects were observed. We suggest that colchicine may be a helpful and safe drug for patients with EBA.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Der Hautarzt 51 (2000), S. 766-769 
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Verruköses Karzinom ; Ackerman-Tumor ; Buschke-Löwenstein-Tumor ; Epithelioma cuniculatum ; Keywords Verrucous carcinoma ; Ackerman's tumor ; Buschke-Löwenstein tumor ; Epithelioma cuniculatum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Verrucous carcinomas represent rare, highly differentiated variants of squamous cell carcinoma. They preferentially develop on the oropharyngeal mucosa (Ackerman tumor), the urogenital mucosa (Buschke-Loewenstein tumors), and the soles of the feet (epitheliomata cuniculata). Various synonyma have been coined for these tumors. We report the uncommon occurrence of a large verrucous carcinoma on apparently uninvolved chest skin of a 79-year old patient. The tumor was excised radically. Complete extirpation was confirmed histologically and there was no sign of recurrence during a 3 month observation period. The clinical appearance, histomorphological features, epidemiological aspects, differential diagnosis, therapy, and nomenclature of verrucous carcinomas are discussed.
    Notes: Zusammenfassung Verruköse Karzinome repräsentieren seltene Sonderformen hochdifferenzierter Plattenepithelkarzinome. Sie treten bevorzugt an der oropharyngealen Mukosa (Ackerman-Tumoren), der urogenitalen Mukosa (Buschke-Löwenstein-Tumoren) und den Fußsohlen (Epitheliomata cuniculata) auf. Verschiedene Synonyme sind gebräuchlich für verruköse Karzinome unterschiedlicher Lokalisation. Wir berichten über das ungewöhnliche Auftreten eines großen verrukösen Karzinoms auf primär unbefallener Brusthaut bei einem 79-jährigen Patienten. Der Tumor wurde, histologisch kontrolliert, vollständig exzidiert, und in der bis jetzt 3-monatigen Nachbeobachtungsphase fand sich kein Anhalt für ein Rezidiv. Anhand dieses Falls werden klinische Erscheinungsformen, histomorphologische Charakteristika, epidemiologische Aspekte, Differenzialdiagnose, Therapie und Nomenklatur verruköser Karzinome diskutiert.
    Type of Medium: Electronic Resource
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