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  • Column liquid chromatography  (5)
  • Aging  (3)
  • Band 3  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Characterization of the anion transport channel protein in human erythrocytes. Induced circular dichroism of inhibitors bound to the anion transport channel
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 856 (1986), S. 11-18 
    Details
    ISSN: 0005-2736
    Keywords: (Erythrocyte membrane) ; Anion transport ; Band 3 ; Circular dichroism ; Transport inhibitor
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(86)90003-9
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Amino acid residues complexed with eosin 5-isothiocyanate in band 3 protein of the human erythrocyte
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 858 (1986), S. 107-117 
    Details
    ISSN: 0005-2736
    Keywords: Amino-acid modification ; Anion transport ; Band 3 ; Circular dichroism ; Sulfate efflux ; pH titration
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(86)90296-8
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  • 3
    Electronic Resource
    Electronic Resource
    Characterization of eosin 5-isothiocyanate binding site in band 3 protein of the human erythrocyte
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Biomembranes 897 (1987), S. 14-24 
    Details
    ISSN: 0005-2736
    Keywords: Anion transport ; Band 3 ; Binding site ; Circular dichroism ; Competitive inhibition ; Eyrthrocyte membrane ; pH titration
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0005-2736(87)90310-5
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  • 4
    Electronic Resource
    Electronic Resource
    Polyglucosan bodies in the digestive tract of the aged dog (1983)
    Springer
    Acta neuropathologica 60 (1983), S. 297-300 
    Details
    ISSN: 1432-0533
    Keywords: Polyglucosan bodies ; Lafora-like bodies ; Aging ; Smooth muscles ; Digestive tract ; Dog
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In our recent studies on aging phenomena in animals, polyglucosan bodies (PGB) were found within the smooth muscle in the digestive tract of aged dogs without neurologic signs. PGB were basophilic, round, or oval bodies which appeared to have a homogenous or concentric shape. Their histochemical properties were characterized by the presence of glucose polymers (polyglucosan). Electron microscopy revealed that PGB were composed mainly of irregularly clustered, short branching filaments measuring about 90 Å in width. PGB were histochemically and ultrastructurally identical to the previously reported Lafora-like bodies in the CNS of aged dogs. PGB were found in all aged dogs and were disseminated throughout the digestive tract, especially in the cecum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691880
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  • 5
    Electronic Resource
    Electronic Resource
    Correlative studies of axonal spheroids and Lafora-like bodies in aged dogs (1979)
    Springer
    Acta neuropathologica 48 (1979), S. 77-81 
    Details
    ISSN: 1432-0533
    Keywords: Aging ; Nucleus gracilis ; Conus medullaris ; Intra-spheroidal Lafora-like bodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The gracile nucleus and conus medullaris, the sites of predilection for spheroids and Lafora-like bodies, were examined light and electron microscopically in 91 dogs ranging from 1 month to 19 years of age. The number of both structures showed a tendency to increase with age. Spheroids have already been found in younger dogs before the appearance of Lafora-like bodies. In the aged dog, intra-spheroidal Lafora-like bodies were occasionally observed. Correlative studies may yield clues on the pathogenesis of aging phenomena in the CNS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691796
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  • 6
    Electronic Resource
    Electronic Resource
    Lafora-like inclusion bodies in the CNS of aged dogs (1978)
    Springer
    Acta neuropathologica 44 (1978), S. 217-222 
    Details
    ISSN: 1432-0533
    Keywords: Lafora-like inclusion bodies ; Aging ; Dog ; High incidence ; Comparative neuropathology ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forty randomly selected dogs, arranged into three groups according to age, were examined light and electron microscopically. Lafora-like inclusion bodies were found in all cases of aged dogs without neurological signs. They appeared as PAS positive, round bodies measuring up to 15μm in diameter. Typically they had central cores and radiating peripheral lines. Electronmicroscopically, the inclusions consisted of irregularly clustered, short branching filaments measuring about 80–120 Å in diameter or of electrondense homogeneous or granular central cores with filamentous peripheral areas and located both in the perikarya and neuronal processes. The inclusions were disseminated all over the brain and spinal cord. The thalamic nuclei, a circumscribed area dorsal to the aqueduct, and the molecular layer of the superior colliculus were the most severely affected. The frequency of the inclusions showed age-dependency; the inclusions were not found in dogs younger than 2 years, but were extensive in all dogs of more than 8 years of age. The occurrence of the inclusions may therefore represent an age-dependent phenomenon. The relationship between the present findings and Lafora's disease is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691070
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Comparison of surface states of chemically modified silicas in aqueous acetonitrile and methanol (1991)
    Springer
    Chromatographia 31 (1991), S. 347-350 
    Details
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Chemically modified silicas ; Surface states ; n-alkylbenzenes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The thermodynamic behaviour of n-alkylbenzenes on chemically modified silicas in reversed-phase liquid chromatography has been examined in acetonitrile-water and methanol-water systems. Plots of the thermodynamic parameters obtained against the organic solvent compositions indicate an interesting trend which implies that the surface states of the chemically modified silicas under the two eluent systems are different.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02262190
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  • 8
    Electronic Resource
    Electronic Resource
    Determination of the specific interaction of disubstituted aromatic compounds on hydrous zirconium oxide-loaded porous polymer resin (1996)
    Springer
    Chromatographia 42 (1996), S. 396-400 
    Details
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Hydrous zirconium oxide ; Porous polymer resin ; Disubstituted phenols ; ortho-Benzoic acid derivatives
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary A porous polymer resin loaded with hydrous zirconium oxide (Zr-gel) was evaluated as a stationary phase for the liquid chromatographic separation of disubstituted aromatic compounds. The prepared Zr-gel was used to separate disubstituted phenols andortho-substituted benzoic acid derivatives in reversed-phase mode. The retention time of catechol was greater than those of other disubstituted phenols; this implies that the Zr-gel has specificity for the phenolic hydroxyl group. The retention behavior ofortho-substituted benzoic acid derivatives on the Zr-gel was also evaluated in reversedphase mode using buffer. Phthalic acid was specifically retained in the vicinity of pH 6.0, which has been regarded as the equal adsorbic point. Similar behavior was also observed for salicylic acid, although the retention time of salicylic acid was less than that of phthalic acid. It seems that the specific retention behavior of hydrous zirconium oxide is a result of complexation with ligands such as hydroxyl and carboxyl groups. The results of this study have revealed that the retention mechanism of hydrous zirconium oxide is a combination of ion exchange and interaction based on complexation with ligands.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02272129
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  • 9
    Electronic Resource
    Electronic Resource
    Evaluation of the influence of the base material loaded with hydrous zirconium oxide gel on the retention behavior of disubstituted benzoic acids (1996)
    Springer
    Chromatographia 43 (1996), S. 79-81 
    Details
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Hydrous zirconium oxide ; Porous polymer resin ; Silica gel ; ortho-Benzoic acid derivatives
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary Silica gel loaded with hydrous zirconium oxide (Zr-gel-S) has been prepared and the influence of the base material on the retention behavior ofo-phthalic acid on the hydrous zirconium oxide was evaluated. The retention behavior of the acid on the Zr-gel-S was compared with that on Zr-gel-5, the polymer-based Zr-gel. Comparable retention behavior,i.e. maximum retention in the vicinity of pH 6, which has been regarded as the equal adsorbic point, was observed for both types of Zr-gel, although there was a large difference in the retention times. The difference in retention on the two types of Zr-gel could be ascribed to nature of the base material. The results in this experiments showed, however, that the specific behavior at pH 6 was an essential characteristic of hydrous zirconium oxide and was not related to the influence of the base materials.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02272826
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  • 10
    Electronic Resource
    Electronic Resource
    Elution behaviour of anions and cations on a mixed-bed stationary phase of anion and cation exchange resins (1995)
    Springer
    Chromatographia 40 (1995), S. 539-544 
    Details
    ISSN: 1612-1112
    Keywords: Column liquid chromatography ; Mixed-bed stationary phase ; Anion and cation exchange resins ; Retention mechanism of anions and cations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Summary The retention mechanism of anions and cations on a mixed-bed column packed with a mixture of strong anion and cation exchange resins has been studied. Organic acids and inorganic anions have showed the same elution behaviour on the mixed-bed column as on a single anion exchange column. In contrast, different elution behaviours for cations have been observed between the mixed-bed column and a single cation exchange column. On the mixed-bed column, cations would be eluted by a mixed retention mechanism. The primary retention mechanism is ion exchange with eluent cation (H+) for all cations. The ion exchange mechanism on the sites occupied by anion exchange groups makes a greater contribution for monovalent cations. A partition mechanism between the stationary phase and mobile phase contributes to the separation of Mg2+ and Ca2+ by forming neutral compounds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02290265
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