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  • Arterio-venous shunt  (1)
  • Contrast enhancement-Brain tumours  (1)
  • 1
    ISSN: 1432-1920
    Schlagwort(e): Tomography, X-ray computed ; Tomography, positron emission ; Contrast enhancement-Brain tumours ; Blood brain barrier ; 68-Ga-EDTA
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Disruption of the blood brain barrier or rather blood tumour barrier in cerebral tumours was studied with CT after intravenous injection of contrast medium and with PET after intravenous administration of 68-Ga-EDTA. Histology from stereotactic biopsies or open surgery is compared with the radiologic findings and advantages of the respective methods are discussed. The material consisted of 47 patients mainly with supratentorial gliomas and a few miscellaneous tumours. Astrocytomas (Kernohan grade II) were found to have no disruption of blood tumour barrier while anaplastic astrocytomas and glioblastomas (Kernohan grade III and IV) had. PET is somewhat superior to CT in detection of disruption of the blood tumour barrier. It is concluded that the combination of CT and PET is of value in the assessment of intracranial tumours.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 0942-0940
    Schlagwort(e): Arterio-venous shunt ; bleeding course ; epidural haematoma ; diploicveins ; absorption capacity ; epidural space ; subarachnoid space ; clinical outcome
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary In order to test the possibility suggested in previous studies that the long bleeding time and the large bleeding volume observed in experimental epidural bleeding can be explained by the development of an arterio-venous shunt, water soluble X-ray contrast was injected into the epidural space in dogs during an epidural bleeding in progress. It was found that the contrast medium left the epidural space through diploic veins in the cranial bone to the neck veins. By draining off epidural blood the arterio-venous shunt counteracts the intracranial pressure tamponade developing in intradural bleeds and thus prolongs bleeding. Perfusion experiments showed the absorption capacity for saline to be about 20 times as large in the epidural space as in the CSF space. While there was no apparent absorption limit for blood in the epidural space the absorption capacity for blood of the subarachnoid space became progressively saturated, leading to a continuously increasing CSF outflow resistance and CSF steady-state pressure. A theory for the formation of epidural haematoma is proposed which in essence implies that the epidural shunt is a major determinant of the clinical outcome of an epidural bleeding.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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