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  • 1995-1999  (3)
  • Glycosylation  (2)
  • Corynomycolic acid  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Effects of fructose ingestion on sorbitol and fructose 3-phosphate contents of erythrocytes from healthy men (1996)
    Springer
    Acta diabetologica 33 (1996), S. 100-102 
    Details
    ISSN: 1432-5233
    Keywords: Fructose 3-phosphate ; Sorbitol ; Erythrocyte ; Glycosylation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To investigate the effect of fructose ingestion on sorbitol and fructose 3-phosphate (F3P) in erythrocytes, we administered 50 g fructose with and without treatment with an aldose reductase inhibitor, epalrestat, to seven healthy, normal-glucose-tolerant, male volunteers aged 20–43 years. The same subjects were given 50 g glucose on another day. The sorbitol and F3P contents in their erythrocytes increased significantly, reaching peak levels at 60 min and 180 min, respectively, following fructose ingestion. On the other hand, glucose ingestion did not cause any statistically significant change in sorbitol content in their erythrocytes, although it significantly elevated their F3P content. Treatment with epalrestat had no significant effect on incremental changes in erythrocyte sorbitol and F3P content following fructose ingestion. This suggests that oral fructose may be converted directly to sorbitol and F3P in erythrocytes instead of being converted via glucose. Thus, the dietary intake of fructose may affect the concentrations of sorbitol and F3P in erythrocytes in normal men.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00569417
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Effects of fructose ingestion on sorbitol and fructose 3-phosphate contents of erythrocytes from healthy men (1996)
    Springer
    Acta diabetologica 33 (1996), S. 100-102 
    Details
    ISSN: 1432-5233
    Keywords: Key words  Fructose 3-phosphate ; Sorbitol ; Erythrocyte ; Glycosylation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract   To investigate the effect of fructose ingestion on sorbitol and fructose 3-phosphate (F3P) in erythrocytes, we administered 50 g fructose with and without treatment with an aldose reductase inhibitor, epalrestat, to seven healthy, normal-glucose-tolerant, male volunteers aged 20–43 years. The same subjects were given 50 g glucose on another day. The sorbitol and F3P contents in their erythrocytes increased significantly, reaching peak levels at 60 min and 180 min, respectively, following fructose ingestion. On the other hand, glucose ingestion did not cause any statistically significant change in sorbitol content in their erythrocytes, although it significantly elevated their F3P content. Treatment with epalrestat had no significant effect on incremental changes in erythrocyte sorbitol and F3P content following fructose ingestion. This suggests that oral fructose may be converted directly to sorbitol and F3P in erythrocytes instead of being converted via glucose. Thus, the dietary intake of fructose may affect the concentrations of sorbitol and F3P in erythrocytes in normal men.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00569417
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Biodetergent IV. Monolayers of corynomycolic acids at the air-water interface (1999)
    Springer
    Colloid & polymer science 277 (1999), S. 334-339 
    Details
    ISSN: 1435-1536
    Keywords: Key words Biomimetic surfactant ; Corynomycolic acid ; Monolayer ; Condensed film ; Alkyl chain length
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The effects of alkyl chain length and of differences in the length of the two alkyl chains on the formation of a monolayer of chemically synthesized corynomycolic acid (2-alkyl-3-hydroxy fatty acid) at the air-water interface were examined. Hydrophobic interactions between the two alkyl chains are required for the formation of a condensed film, which is most stable when the total number of carbon atoms in the two alkyl chains is 25 or more and the difference in their lengths is one. Syn-isomers form condensed films but usually not anti-isomers. However, films may also be formed by the anti-isomer when the alkyl chain at the carboxy group (the 2-position) is longer than the alkyl chain at the hydroxy group (the 3-position). That is, the contribution of anti-isomers to condensed film formation depends on the polar carboxy group which has greater involvement in this formation. The extrapolated area for the condensed film of corynomycolic acid was 40 Å2 per molecule, thus confirming that both the carboxy and hydroxy groups are present on the water surface when a bipolar monolayer is formed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050389
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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