ISSN:
1432-0584
Schlagwort(e):
Human hematopoietic progenitor cells
;
Cytokines
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Summary The concept of ex vivo expansion of the human progenitor cell population was tested in this study. In the presence of interleukin-3 and -6 we compared the abilities of various liquid culture conditions of human blood-derived hematopoietic progenitor cells to yield a suitable condition for the expansion of blood progenitor cells. Although the best result was obtained in the gas-permeable bag culture system, the enhancement effect (maximum of 3.8-fold for granulocyte/macrophage colony-forming units and 3.0-fold for erythroid burst-forming units) lasted for only a short period (〈 6 d). The results of this study are disappointing for clinical use, and attempts with currently available technology appear to be limited in their potential.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01738299
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