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  • 1975-1979  (2)
  • Desmethyltrichlorphone  (1)
  • Organic Chemistry  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Zur Mutagenität von Desmethyl-Trichlorphon im Dominanten-Letal-Test an der Hausmaus (1975)
    Springer
    Archives of toxicology 33 (1975), S. 163-168 
    Details
    ISSN: 1432-0738
    Keywords: Trichlorphone ; Desmethyltrichlorphone ; Mutagenic Effect ; Alkylating Properties ; Trichlorphon ; Desmethyl-Trichlorphon ; Mutagene Wirkung ; Alkylierende Eigenschaften
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Nach i.p.-Applikation einer einmaligen Dosis von 405 mg/kg Desmethyl-Trichlorphon (Natriumsalz) sowie von 54 mg/kg täglich über 3 Wochen an AB-Mäuse war die mutagene Wirkung im Dominanten-Letal-Test mindestens ebenso groß wie nach Applikation von Trichlorphon in gleicher Dosierung. Diesem Befund zufolge scheint die genotoxische Wirkung des Trichlorphons nicht ausschließlich im Zusammenhang mit seinen alkylierenden Eigenschaften zu stehen.
    Notes: Abstract After i.p. administration to AB mice of 405 mg/kg desmethyltrichlorphone (sodium salt) in a single dose and 54 mg/kg daily for 3 weeks, the mutagenic effect in the dominant lethal test was at least the same as that of trichlorphone. These findings indicate that the genotoxic effect of trichlorphone is not likely to be due to its alkylating properties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00353241
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Reaktionen von 2,3-Dichlormaleinimiden mit methylenaktiven Verbindungen (1979)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 321 (1979), S. 787-796 
    Details
    ISSN: 0021-8383
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Reactions of 2,3-Dichloromaleimides with Methyleneactive Compounds2,3-Dichloromaleimides 1 react with activated methylene compounds mainly under monosubstitution to give 2-6. Replacement of the second chloroatom gives 2,3-disubstituted maleimides 9-15 and stable ylides 16-27 with pyridine and triphenylphosphine, respectively. A general synthesis for such maleimid-ylides was found in a one-batch reaction from 2,3-dichloromaleimides 1 with methyleneactive compounds and pyridine or triphenylphosphine.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prac.19793210510
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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