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  • 32.30.Jc  (1)
  • Dorsal horn  (1)
  • 1
    ISSN: 1432-1106
    Keywords: Dorsal column nuclei ; Gracile nucleus ; Primary sensory neuron ; Dorsal horn ; Glia ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The time course of the microglial cell reaction in central nervous system primary sensory projection territories has been examined following peripheral nerve injury in the adult rat using qualitative and quantitative analysis of immunoreactivity with the monoclonal antibody OX-42, which recognises the complement receptor CR3. The regions examined included the gracile nucleus, the column of Clarke and the spinal cord dorsal horn (superficial and deep laminae separately) after unilateral sciatic nerve transection, and the spinal trigeminal nucleus following unilateral infraorbital nerve transection. In all territories examined a qualitative increase in OX-42 immunoreactivity was observed 24 h postlesion. Further, quantitative analysis revealed an exponential development of the OX-42 immunoreactivity, with a peak at one week postlesion, thereafter showing a slow exponential decline. Our results show that the signal (or signals) that induces the microglial cell response in primary sensory projection territories is rapid in comparison to previously described central degenerative changes following peripheral nerve lesions (transganglionic degeneration). These findings are compatible with the hypothesis that activated microglia play a pathogenetic role in the development of transganglionic degeneration.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 98 (1995), S. 353-357 
    ISSN: 1434-6036
    Keywords: 32.30.Jc ; 32.70.Fw ; 67.40.Yv
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Optical spectra and radiative lifetimes of neutral atoms in superfluid helium have been studied. The absorption and emission spectra of Ag, Mg, Yb, Al, Ga, and In were found to exhibit shifts and broadening typical of atoms residing in microscopic He bubbles, showing that this type of trapping is fairly general. The radiative lifetimes measured for these atoms are close to the free space values, indicating that the surrounding bubble hardly perturbs the electronic orbitals during photo emission. One exception observed in Sr is discussed, where competing autoionization substantially decreases the lifetime of a high excited triplet state. A transient non-bubble state with sharp, free atom like spectra is seen during the first few μs after dispersion for many atomic species. The dynamics of this state are unusual, with for example very short radiative lifetimes measured for light alkali atoms.
    Type of Medium: Electronic Resource
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