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Intrasellar hamartoma associated with pituitary adenoma (1990)

Slowik, F. ; Fazekas, I. ; Bálint, K. ; [et al.]

Springer

Acta neuropathologica 80 (1990), S. 328-333

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ISSN: 1432-0533

Keywords: Pituitary adenoma ; Neuronal and lipomatous hamartoma ; Immunocytochemistry ; Electron micrscopy

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The histological, ultrastructural and immunocytochemical features are reported of an intrasellar neuronal and lipomatous hamartoma associated with pituitary growth hormone (GH) cell adenoma and acromegaly. Electron microscopy demonstrated a close contact between neurons and adenomatous GH cells. By immunohistochemistry the adenoma cells revealed a positive staining for GH and prolactin. the neurons of hamartoma showed neurosecretory activity which might have induced the development of pituitary GH cell adenoma.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00294652

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