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  • Choline acetyltransferase  (1)
  • Enzymes  (1)
  • Metabolism  (1)
  • PACS: 25.55.Kr 2H-,3He- and 4He-induced charge exchange reactions – 14.20.Gk Baryon resonances with S = 0 – 24.10.Eq Coupled channel and distorted wave models  (1)
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  • 1
    Digitale Medien
    Digitale Medien
    Altered brain cholinergic enzymes activity in the genetically obese rat (1991)
    Springer
    Cellular and molecular life sciences 47 (1991), S. 833-835 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Choline acetyltransferase ; acetylcholinesterase ; obesity
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Genetically obese male Zucker rats (fa/fa) and their lean littermates (Fa/-) were used in this experiment. Fourteen-week-old obese and lean littermates were sacrificed and choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) enzymes were assayed in specific brain regions. The assays of these enzymes indicate that obese animals and a significantly lower ChAT activity in the cerebellum, pons, and cerebral cortex and a significant increase in ChAT activity in the thalamus and hypothalamus. Meanwhile, the cerebral cortex, cerebellum, midbrain, thalamus and hypothalamus of the obese animals showed significantly higher AChE activity than their lean littermates. It was concluded from this study that obesity may be associated with changes in the enzymes of the brain cholinergic system.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01922466
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  • 2
    Digitale Medien
    Digitale Medien
    Inclusive 2(3He,t) reaction at 2 GeV (1999)
    Springer
    The European physical journal 6 (1999), S. 225-233 
    Details
    ISSN: 1434-601X
    Schlagwort(e): PACS: 25.55.Kr 2H-,3He- and 4He-induced charge exchange reactions – 14.20.Gk Baryon resonances with S = 0 – 24.10.Eq Coupled channel and distorted wave models
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract: The inclusive 2(3He,t) reaction has been studied at 2 GeV for energy transfers up to 500 MeV and scattering angles from 0.250 up to 40. Data are well reproduced by a model based on a coupled-channel approach for describing the NN and NΔ systems. The effect of final state interaction is important in the low energy part of the spectra. In the delta region, the cross-section is very sensitive to the effects of Δ-N interaction and ΔN → NN process. The latter has also a large influence well below the pion threshold. The calculation underestimates the experimental cross-section between the quasi-elastic and the delta peaks; this is possibly due to projectile excitation or purely mesonic exchange currents.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s100500050338
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  • 3
    Digitale Medien
    Digitale Medien
    Y-intercept of the maximal work-duration relationship and anaerobic capacity in cyclists (1994)
    Springer
    European journal of applied physiology 69 (1994), S. 550-556 
    Details
    ISSN: 1439-6327
    Schlagwort(e): Muscle ; Metabolism ; Enzymes ; Buffer value
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The degree to which the y-intercept (Y-int) of the linear regression of maximal work output on exercise duration represented anaerobic capacity was determined in ten well-trained male cyclists [peak oxygen uptake ( $$\dot V{\text{O}}_{{\text{2peak}}} $$ = 69.8 (SD 4.2) ml · kg −1 · min −1). Each cyclist performed three exhausting cycle sessions on separate occasions; the mean exercise durations were 312, 243 and 141 s for the low (approximately 104% $$\dot V{\text{O}}_{{\text{2peak}}} $$ , medium (approximately 108% $$\dot V{\text{O}}_{{\text{2peak}}} $$ and high (approximately 113% $$\dot V{\text{O}}_{{\text{2peak}}} $$ intensities respectively, and Y-int (kilojoules; joules per kilogram was derived from the regression of work output on exercise duration. The muscle anaerobic adenosine 5′-triphosphate (ATP) yield (ΣATP) and anaerobic capacity (AC) were estimated from changes in metabolites in the vastus lateralis muscle and blood lactate concentration during the high intensity cycling session. The activities of glycogen phosphorylase, phosphofructokinase and citrate synthase, as well as muscle buffer value (in vitro β) were also determined. The Y-int (kilojoules) was positively correlated (P≤0.05) with AC (r=0.73), ΣATP (r=0.70) and in vitro β (r=0.71); similar correlations (P≤0.05) were observed for Y-int (joules per kilogram). The Y-int was not correlated (P〉0.05) with any enzyme activity. When the Y-int was transformed into oxygen equivalents [litres of oxygen equivalent (1 O2 Eq)] it was, on average, 0.92 1 O2 Eq lower than AC (P≤0.05); however, an alternative method of establishing the work-duration regression yielded a mean Y-int which was only 0.19 1 O2 Eq less than AC (P≥0.05). These findings support the validity of Y-int as a work estimate of anaerobic capacity in well-trained cyclists.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00239874
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