ISSN:
1573-2622
Keywords:
Electroretinogram
;
Hydroxocobalamin
;
Tobacco amblyopia
;
Visual acuity
;
F.M. 100 Hue test
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract In seven recently diagnosed and untreated patients with tobacco amblyopia the light and dark adapted electroretinograms were recorded together with visual acuity, central fields and the Farnsworth-Munsell 100-Hue test. After 3 months treatment with injections of hydroxocobalamin all these tests were repeated. An improvement in visual acuity resulted in all cases. A significant reduction in the Farnsworth-Munsell total error score of the seven patients was noted (p 〈 0.01). A significant increase in the amplitude of the light adapted b-wave of the ERG was found (0.01 〈 p 〈 0.02) following the course of hydroxocobalamin injections. No other significant changes in the ERG were demonstrated. It is suggested that the ERG changes demonstrated an improvement in an abnormal biochemical state in those bipolar and perhaps Müller cells of the inner nuclear layer of the retina which make electrophysiological connections chiefly with foveal cones.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00142622
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