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  • 1
    ISSN: 1432-1106
    Schlagwort(e): Spinal cord ; H-reflexes ; Ia afferents ; Motoneurones ; Human
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The size of the soleus H-reflex was measured after a slow (17 deg/s) passive stretch of ankle plantarflex ors and compared to its control size without muscle stretch in ten neurologically healthy subjects and in six spastic spinal-cord-injured patients. Two seconds after the end of the stretch, the size of the H-reflex was reduced to about 30% of its pre-stretch size in the healthy sub jects. The depression remained for 10–15 s. In the spastic, spinal-cord-injured patients, stretch caused significantly less reduction in the size of the H-reflex. The H-reflex also regained its pre-stretch size much faster than in healthy subjects. We suggest that the smaller depression of the H-reflex observed in spastic patients may be involved in the pathophysiology of spasticity.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 120 (1998), S. 143-152 
    ISSN: 1432-1106
    Schlagwort(e): Key words Somatosensory evoked potential ; Gating ; H-reflex ; Voluntary movement ; Human
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Somatosensory evoked potentials (SEPs) evoked by stimulation of the tibial nerve (TN) in the popliteal fossa, the sural nerve (Sur) at the lateral malleole, and an Achilles tendon (Achilles) tap were recorded before and during voluntary plantarflexion, dorsiflexion, and cocontraction of the ipsi- and contralateral foot in normal subjects. Suppression (gating) of the TN-SEP began around 60 ms before the onset of electromyographic activity (EMG), and became maximal 50–100 ms after the onset of EMG. Similar gating was observed for the SEP evoked by activation of muscle afferents (Achilles) and cutaneous afferents (Sur). The TN-SEP was similarly depressed at the onset of a plantarflexion as at the onset of dorsiflexion. A depression, although much smaller, was also observed at the onset of movement of the contralateral limb. The depression of the TN-SEP after the onset of EMG decreased when fast-conducting afferents were blocked by ischemia below the knee joint. The TN-SEP was equally depressed during tonic dorsiflexion, plantarflexion, and cocontraction of dorsi- and plantarflexors. The TN-SEP was depressed for up to 300 ms when preceded by stimulation of Sur or a biceps femoris tendon tap. Gating of lower limb SEPs thus appears to have both central and peripheral components of which neither seems to be specific for the muscle being contracted or the sensory afferents being stimulated. We encourage that caution is taken when drawing functional conclusions regarding movement-specific modulation of afferent inflow to the somatosensory cortex based on observations of gating of lower limb SEP.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    ISSN: 1437-1596
    Schlagwort(e): Blutgruppen ; GPT und SEP
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin , Rechtswissenschaft
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Es wird über quantitative Untersuchungen der einzelnen Phänotypen der Isoenzyme Glutamat-Pyruvat-Transaminase (GPT) und der sauren Erythrocytenphosphatase (SEP) berichtet. An Hand der Ergebnisse wird die Möglichkeit der Diagnose eines sog. stummen Genes und ihre forensische Verwertbarkeit in der Paternitätsserologie diskutiert. Auf Grund einer erheblichen Streubreite der „Normalwerte“ der Aktivitäten der einzelnen GPT-Phänotypen ist GPTo nicht mit der erforderlichen Sicherheit zu erkennen. Für das SEP-System wird ein Verfahren beschrieben, welches für die Paternitätsserologie unter praktikablen Bedingungen eine forensisch verwertbare Diagnose SEPo erlaubt. Nach Auffassung der Autoren ist in einem Falle isolierter, entgegengesetzter Reinerbigkeit im SEP-System stets eine quantitative Untersuchung erforderlich.
    Notizen: Summary A report is made on quantitative investigations of single phenotypes of red cell glutamic-pyruvic transaminase (GPT) and of red cell acid phosphatase (SEP). On the basis of the results, the possibility of the diagnosis of a so-called “silent gene” and its possible forensic use in paternity cases are discussed. On the strength of a considerable dispersion of the “normal values” of the activities found in each single GPT phenotype, GPTo cannot be recognized by this method with the certainty required. For the SEP system a process is described which produces a forensically serviceable diagnosis SEPo in paternity cases. According to the conception of the authors a quantitative investigation is always essential in a case of isolated opposite homozygosity in the SEP system.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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