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  • 1
    Electronic Resource
    Electronic Resource
    Effect of neonatal monosodium glutamate on the activities of glutamate dehydrogenase and aminotransferases in the circumventricular organs of rat brain (1995)
    Springer
    Amino acids 8 (1995), S. 393-395 
    Details
    ISSN: 1438-2199
    Keywords: Amino acids ; Monosodium glutamate ; Glutamate dehydrogenase ; Aminotransferases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Glutamate (Glu) the major amino acid in mammalian brain and most dietary proteins possesses neurotransmitter as well as neurotoxic properties. We administered monosodium glutamate (MSG) 4 mg/g bwt, sc on postnatal day (PND) 1 through 10 to rats on alternate days or daily and sacrificed them on PND 45 or PND 90 respectively. The activities of glutamate dehydrogenase and aminotransferases were evaluated in the circumventricular organs of brain. Results show that neonatal MSG produces alterations in glutamate metabolism in blood-brain-barrier deficient regions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00806557
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Topographical Multilevel Single Linkage (1994)
    Springer
    Journal of global optimization 5 (1994), S. 349-358 
    Details
    ISSN: 1573-2916
    Keywords: Global optimization ; multilevel single linkage ; topographs ; graph minima
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract An iterative topographical Multilevel Single Linkage (TMSL) method has been introduced. The approach uses topographical information on the objective function, in particular theg-nearest-neighbour graph. The algorithm uses evenly distributed points from a Halten sequence of uniform limiting density. We discuss the implementation of the algorithm and compare its performance with other well-known algorithms. The new algorithm performs much better (in some cases several times) than the Multilevel Single Linkage method in terms of number of function evaluations but is not quite so competitive with respect to CPU time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01096684
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    A Numerical Comparison of Some Modified Controlled Random Search Algorithms (1997)
    Springer
    Journal of global optimization 11 (1997), S. 377-385 
    Details
    ISSN: 1573-2916
    Keywords: Global optimization ; β-distribution ; controlled random search
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract In this paper we propose a new version of the Controlled Random Search(CRS) algorithm of Price. The new algorithmhas been tested on thirteen global optimization test problems. Numericalexperiments indicate that the resulting algorithm performs considerablybetter than the earlier versions of the CRS algorithms. The algorithm,therefore, could offer a reasonable alternative to many currently availablestochastic algorithms, especially for problems requiring ’direct search‘type methods. Also a classification of the CRS algorithms is made based on’global technique‘ – ’local technique‘ and the relative performance ofclasses is numerically explored.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008236920512
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Application of Stochastic Global Optimization Algorithms to Practical Problems (1997)
    Springer
    Journal of optimization theory and applications 95 (1997), S. 545-563 
    Details
    ISSN: 1573-2878
    Keywords: Global optimization ; real life problems ; pig liver likelihood function ; many-body potential function ; tank reactor ; optimal control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract We describe global optimization problems from three different fields representing many-body potentials in physical chemistry, optimal control of a chemical reactor, and fitting a statistical model to empirical data. Historical background for each of the problems as well as the practical significance of the first two are given. The problems are solved by using eight recently developed stochastic global optimization algorithms representing controlled random search (4 algorithms), simulated annealing (2 algorithms), and clustering (2 algorithms). The results are discussed, and the importance of global optimization in each respective field is focused.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1022617804737
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Aspiration Based Simulated Annealing Algorithm (1997)
    Springer
    Journal of global optimization 11 (1997), S. 181-191 
    Details
    ISSN: 1573-2916
    Keywords: Global optimization ; continuous variables ; aspiration value ; simulated annealing ; stochastic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract An aspiration based simulated annealing algorithm for continuousvariables has been proposed. The new algorithm is similar to the one givenby Dekkers and Aarts (1991) except that a kind of memory is introduced intothe procedure with a self-regulatory mechanism. The algorithm has beenapplied to a set of standard global optimization problems and a number ofmore difficult, complex, practical problems and its performance comparedwith that of the algorithm of Dekkers and Aarts (1991). The new algorithmappears to offer a useful alternative to some of the currently availablestochastic algorithms for global optimization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008202703889
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    Paper (German National Licenses)
    Fulltext
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