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  • 1
    ISSN: 0942-0940
    Keywords: Glucocorticoid receptor ; brain tumour ; malignant astrocytomas ; steroid treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Glucocorticoid receptors were measured in tissue samples from 12 patients with glioblastoma multiforme. The receptor was found in all patients. The concentration of glucocorticoid receptor was found to be high in the periphery of the tumour, low in the surrounding brain tissue and low in the central part of the tumour in 6 of the patients. The possible role of the glucocorticoid receptor distribution in relation to growth regulation is discussed. A decreasing receptor concentration found at reoperation in two patients indicates a possible antineoplastic effect of high dose methylprednisolone pulse therapy on glucocorticoid receptor positive glioblastomas.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1433-3023
    Keywords: Bladder ; Continence ; Levator ani ; Physiotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The dynamic anatomical response of the normal pelvic floor to voluntary pelvic floor contractions was documented using magnetic resonance imaging. Sequences of coronal, sagittal and transverse images in the relaxed and the contracted state were obtained from 17 young, asymptomatic volunteers trained to perform pelvic floor exercises correctly. The images were processed digitally and computer colored to indicate dynamic changes produced as a result of contractions. Gross transverse sections through a human female cadaver were photographed and digitized to provide a reference of pelvic anatomy. A 3D rendition of the processed MR images was made to illustrate the extent of pelvic floor contraction. The results illustrate the changes produced by voluntary pelvic floor contractions in all planes scanned. Quantitative measurements of selective structures around the bladder were made to show the magnitude of pelvic floor displacement during contraction. The dynamic imaging illustrates the extent of changes in the normal pelvic floor that are produced by pelvic floor exercises and give a measure of the displacement of the bladder and the levator ani.
    Type of Medium: Electronic Resource
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