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Detection of herpes simplex virus DNA in a cutaneous squamous cell carcinoma by in situ hybridization (1989)

Claudy, A. L. ; Chignol, M. C. ; Chardonnet, Y.

Springer

Archives of dermatological research 281 (1989), S. 333-335

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ISSN: 1432-069X

Keywords: Squamous cell carcinoma ; Herpes simplex virus ; In situ hybridization ; Virus and cancer

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary A case of a cutaneous squamous cell carcinoma (SCC) occurring at the site of a long-standing recurrent HSV infection is described. No deficit of the cell-mediated immunity was recorded. HSV2 was isolated in several viral cultures. HSV DNA was visualized in the SCC by in situ hybridization with biotinylated probes in paraffin-embedded tissue. The samples were negative for HPV2, 5, 16, and 18 probes. A causal relationship between HSV infection and cutaneous SCC is hypothesized.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00412977

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