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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 20 (1972), S. 335-347 
    ISSN: 1432-0533
    Keywords: Spinal Cord Ischemia ; Neurons ; Glycogen ; UDPG-transferase ; Glycogen Phosphorylase ; Histochemistry ; Electron Microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Partial ischemia of the spinal cord in adult cats was induced by abdominal aortic ligation. The most striking abnormality was an accumulation of glycogen in large motor neurons and astroglia in the peripheral anterior horns. Little or no histological and ultrastructural abnormalities were present in these regions. The first glycogen deposits appeared after 1/2 h in glial cells, whereas glycogen accumulation in neurons was first noticeable 1 h after ligation reaching a maximum in 24 h. A gradual decrease occurred with disappearance of glycogen at 10 days. Increase in UDPG-transferase was found preceeding glycogen appearance, and increase in glycogen-phosphorylase activity occurred later concurrent with glycogen accumulation. This unique neuronal glycogen deposition may be due to the UDPG-transferase normally present in γ-motor neurons of the anterior horns. Other possible mechanisms are also considered.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 22 (1972), S. 158-169 
    ISSN: 1432-0533
    Keywords: Brain Stab Wound ; Glycogen Reaction ; Histochemistry ; Electron Microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Abnormal accumulation of glycogen around cerebral stab wounds was studied histochemically, electron microscopically, and quantitatively in rats 4, 13, 28 days old and in adult (90–150 days old) animals. Glycogen did not accumulate around stab wounds in 4 and in 13-day old rats, whereas a considerable accumulation of glycogen was present in the 28 day and in adult animals. There was a close parallelism between the amount of glycogen accumulated and the degree of maturation of oxidative enzyme activity as reflected by succinic dehydrogenase activity in the cortex. In 28 day and in adult animals, a pale central necrotic core was surrounded by a zone of reduced enzyme activity. The region of glycogen accumulation was located peripherally to this zone.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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