ISSN:
1432-2307
Keywords:
Giant cell tumor
;
Ultrastructure
;
Alkaline phosphatase
;
Human bone neoplasias
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The fine structural localization of nonspecific alkaline phosphatase was elucidated in two giant cell tumors of bone using lead as capturing ion and Β-glycerophosphate as substrate in the incubation solution. Lead phosphate precipitate — indicating presence of alkaline phosphatase — was demonstrated on the plasma membranes, and the membranes bordering vesicles and vacuoles of presumed endocytotic nature, in giant cells and type 1 stromal cells (fibroblast-like cells). The findings support the view that stromal cells type I and giant cells are histogenetically related.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00465595
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