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  • 1
    Electronic Resource
    Electronic Resource
    Clinical settings and vasopressin function in hyponatraemic children (1993)
    Springer
    European journal of pediatrics 152 (1993), S. 301-305 
    Details
    ISSN: 1432-1076
    Keywords: Hyponatraemia ; Syndrome of inappropriate antidiuretic hormone secretion ; Vasopressin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Hyponatraemia is one of the most common electrolyte abnormalities in hospitalised children. In a prospective study we tested whether hyponatraemia is associated with sustained release of the antidiuretic hormone arginine vasopressin (AVP). Out of 27 children with persistent hyponatremia (serum sodium 〈130 mmol/l), 25 had measurable plasma concentrations of AVP [median and quartiles 5.0 pg/ml (1.5–8.3)]. Volume contraction as consequence of sodium loss caused hyponatraemia in 16 patients. Hyponatraemia in the presence of extracellular volume expansion and reduced effective arterial blood volume occurred in 5 patients. Only 3 patients had normovolaemic hyponatraemia (so-called syndrome of inappropriate antidiuretic hormone secretion) and 3 suffered from chronic renal failure. It is concluded that plasma AVP concentration is measurable in most children with hyponatraemia. Non-osmotic stimulation of AVP release and lack of suppression of this hormone is an important pathogenetic mechanism of hyponatraemia in children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01956738
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Hyponatraemia and hyperkalaemia in acute pyelonephritis without urinary tract anomalies (1995)
    Springer
    European journal of pediatrics 154 (1995), S. 582-584 
    Details
    ISSN: 1432-1076
    Keywords: Pyelonephritis ; Hyponatraemia ; Hyperkalaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Abstract Three children with severe hyponatraemia and hyperkalaemia associated with acute pyelonephritis are reported. All were very young male infants in a poor general condition and seriously dehydrated. Diagnostic procedures did not detect obstructive uropathy or vesico-ureteric reflux. Conclusion Hyponatraemia and hyperkalaemia occurs in young infants with severe acute pyelonephritis in the absence of obstructive uropathy or vesico-ureteric reflux. The severe inflammation of the kidney itself may explain the electrolyte disturbance by a transient resistance of the distal tubule to aldosterone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02074840
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Hyponatraemia and hyperkalaemia in acute pyelonephritis without urinary tract anomalies (1995)
    Springer
    European journal of pediatrics 154 (1995), S. 582-584 
    Details
    ISSN: 1432-1076
    Keywords: Key words Pyelonephritis ; Hyponatraemia ; Hyperkalaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Three children with severe hyponatraemia and hyperkalaemia associated with acute pyelonephritis are reported. All were very young male infants in a poor general condition and seriously dehydrated. Diagnostic procedures did not detect obstructive uropathy or vesico-ureteric reflux. Conclusion Hyponatraemia and hyperkalaemia occurs in young infants with severe acute pyelone-phritis in the absence of obstructive uropathy or vesico-ureteric reflux. The severe inflammation of the kidney itself may explain the electrolyte disturbance by a transient resistance of the distal tubule to aldosterone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02074840
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Increased kallikrein excretion in spontaneously hypertensive rats and its inhibition by 6-hydroxydopamine (1980)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 313 (1980), S. 155-157 
    Details
    ISSN: 1432-1912
    Keywords: Spontaneosly hypertensive rats ; Urinary kallikrein ; Sympathetic activity ; 6-Hydroxydopamine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Urinary kallikrein excretion was studied in young, stroke-prone, spontaneously hypertensive rats (spSHR). Seven-week-old spSHR were found to excrete more kallikrein into the urine than normotensive Wistar Kyoto control rats (WKR). “Chemical sympathectomy”, induced by 6-hydroxydopamine (6-OHDA) immediately after birth, resulted in normotensive blood-pressure levels and in a reduction of kallikrein in spSHR. In normotensive WKR, blood pressure and urinary kallikrein excretion were only slightly diminished by 6-OHDA. The results suggest a relationship between sympathetic activity and kallikrein excretion, being especially pronounced in spSHR, which have an elevated sympathetic activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00498573
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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