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Digitale Medien

Immunoglobulin class of rheumatoid factors detected by enzyme-linked immunosorbent assay (1983)

Nishimaki, T. ; Watanabe, S. ; Yoshida, H. ; [weitere]

Springer

Clinical rheumatology 2 (1983), S. 145-151

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ISSN: 1434-9949

Schlagwort(e): IgG-Rheumatoid factor ; IgA-Rheumatoid factor ; Enzyme Immunoassay ; Rheumatic Diseases

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary The immunoglobulin class of rheumatoid factor (RF) in sera and synovial fluids of patients with rheumatic diseases was measured by a solid-phase enzyme immunoassay. IgG-RF was frequently found in seronegative sera as well as in seropositive sera of rheumatic patients. Titers of IgG-RF were higher in the active phase than in the inactive phase of SLE and showed a correlation to the levels of hypocomplementemia and circulating immune complexes in SLE sera. Titers of IgA-RF were likewise higher in the active-phase of SLE with a correlation to titers of circulating immune complexes. IgA-RF was also found frequently in sera of patients with Sjögren's syndrome.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02032171

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