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  • 1
    Electronic Resource
    Electronic Resource
    Effects of dopamine on whole kidney function and proximal transtubular volume fluxes in the rat (1977)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 296 (1977), S. 289-292 
    Details
    ISSN: 1432-1912
    Keywords: Renal transport ; Dopamine ; β-Adrenoreceptors ; Micropuncture ; Renal blood flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The renal effects of dopamine were studied using clearance and micropuncture techniques in rats. Intravenous infusion of dopamine (4.7 · 10−6 mol · kg−1 · h−1) increased glomerular filtration rate and renal blood flow. Renal blood flow was measured by an electromagnetic flowmeter. The increase in filtered fluid and sodium was nearly completely matched by increased tubular reabsorption. Thus, only a small rise in urine flow and in urinary sodium excretion was observed. The micropuncture experiments using the split oil droplet method of Gertz demonstrated a stimulation of the transepithelial fluid transfer after injection of dopamine (10−4M) into the proximal tubular lumen. This effect was abolished by simultaneous injection of propranolol (10−3 M) which, by its own, did not affect transtubular volume fluxes. It is concluded that dopamine, by stimulation of β-adrenoceptors, may increase reabsorptive capacity of the proximal tubular epithelium independent of changes in renal hemodynamics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00498695
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  • 2
    Electronic Resource
    Electronic Resource
    Action of the competitive angiotensin II antagonist saralasin during the initial phase of glycerol-induced acute renal failure of the rat (1977)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 301 (1977), S. 139-143 
    Details
    ISSN: 1432-1912
    Keywords: Renal function ; Renal blood flow ; Glomerular filtration rate ; Urine volume ; Urinary sodium excretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of the competitive angiotensin II antagonist saralasin (1-sarcosine-8-alanine-5-isoleucine-angiotensin II) on renal function in healthy rats and in rats with myohemoglobinuric acute renal failure were studied. Acute renal failure was induced by an intramuscular injection of 50% glycerol (10 ml ·kg−1). Functional impairment of the glycerol treated animals consisted in a decrease of renal blood flow (electromagnetic flowmeter) and GFR and in an increase of urine volume and arterial blood pressure. In healthy rats saralasin (6 μg·kg−1·min−1 i.v.) had no renal effects by itself but antagonized the angiotensin II (200 ng·kg−1·min i.v.) induced fall of renal blood flow and GFR and the increase of arterial blood pressure. Given to glycerol treated animals saralasin did not induce any change of arterial blood pressure, renal blood flow, GFR or the urinary excretion of fluid and sodium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00501429
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  • 3
    Electronic Resource
    Electronic Resource
    Renal effects of furosemide in glycerol induced acute renal failure of the rat (1976)
    Springer
    Pflügers Archiv 365 (1976), S. 81-87 
    Details
    ISSN: 1432-2013
    Keywords: Renal failure ; Micropuncture ; Diuretics ; Glomerular filtration rate ; Effective filtration pressure ; Renal blood flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The renal effects of furosemide in acute renal failure of the rat were studied using clearance and micropuncture techniques. Acute renal failure was induced by an intramuscular injection of 50% glycerol (10 ml/kg). Functional impairement of the glycerol treated animals consisted of a decrease in urinary sodium excretion, renal blood flow, total kidney GFR and effective filtration pressure of superficial nephrons. Effective filtration pressure was calculated from proximal free flow and stop flow pressure measurements. In contrast to control animals furosemide did not increase urine volume during acute renal failure due to a marked fall in GFR. Renal blood flow, as measured by an electromagnetic flowmeter, also decreased after furosemide in glycerol treated rats and increased in control animals. Furosemide reduced effective filtration pressure during acute renal failure to almost zero, whereas in control animals effective filtration pressure virtually remained constant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00583631
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  • 4
    Electronic Resource
    Electronic Resource
    Ein neuer Beitrag zur Phosphazoreaktion (1973)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 399 (1973), S. 225-230 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: A New Contribution to the Phosphazo ReactionThe reaction of acrylonitrile with phosphorus pentachloride gives ClCH2CCl2CCl2NPCl3 (I) and a hexachlorophosphate with the composition C3H2Cl14NP3 (II). For the first time the structure of (II) has been exactly determined by using 1H- and 31P-NMR-spectra. The course of reaction was studied in detail. 3-chloropropionitrile has been found as the product of a secondary reaction. The reaction of butyramide with PCl5 has also been investigated, and was found to be analogous.
    Notes: Bei der Umsetzung von Acrylnitril mit PCl5 entsteht neben ClCH2CCl2CCl2NPCl3 (I) auch das Hexachlorophosphat mit der Zusammensetzung C3H2Cl14NP3 (II). Die Struktur von (II) konnte durch 1H- und 31P-NMR-Untersuchungen erstmals eindeutig bestimmt werden. Der gesamte Reaktionsablauf wurde untersucht. Infolge einer Sekundärreaktion entsteht u. a. 3-Chlorpropionitril. Die Umsetzung von Butyramid mit PCl5 wird ebenfalls beschrieben. Sie zeigt einen analogen Verlauf.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19733990213
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  • 5
    Electronic Resource
    Electronic Resource
    Untersuchungen über Phosphazoverbindungen aus Anilinen mit PhosphorpentachloridFrau Professor Margot Becke-Goehring zum 60. Geburtstage gewidmet (1974)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 406 (1974), S. 214-220 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Investigations on Phosphazo Compounds from Anilines with Phosphorus PentachlorideThe reaction of anilines with PCl5 gives the monomer compound ArNPCl3. This will dimerize in many cases to (ArNPCl3)2. There are no indications for the former postulated intermediate product ArNHPCl4. We can correlate the tendency to dimerize with the basicity of the anilines. This is confirmed by the measurements of the constants of basicity in acetonitrile.
    Notes: Bei der Reaktion von Anilinen mit PCl5 entsteht die monomere Verbindung ArNPCl3. Diese dimerisiert in vielen Fällen zu (ArNPCl3)2. Für die früher postulierte Zwischenstufe ArNHPCl4 gibt es keine Hinweise. Die Neigung zur Dimerisation ist mit der Basizität der Aniline korrelierbar. Dies wird durch die Messung der Basenkonstanten in Acetonitril bestätigt.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19744060213
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  • 6
    Electronic Resource
    Electronic Resource
    Strukturchemie titan-organischer Verbindungen: Die Struktur von [(π-C5H5)2 Ti(NO3)]2O (1981)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 479 (1981), S. 113-118 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Structural Chemistry of Organotitanium Compounds: Structure of [(π-C5H5)2Ti(NO3)]2OCareful hydrolysis of (π-C5H5)2Ti(NO3)2 in tetrahydrofuran yields crystals of [(π-C5H5)2Ti(NO3)]2O (A). Crystal data of A: monoclinic, space group P21/c; lattice constants: a = 12.656(4), b = 10.181(5), c = 16.197(3) Å, ß = 93.57(3)º, Z = 4. As an X-ray analysis shows, the NO3 groups act as monodentate ligands with Ti—O distances of 2.085 and 2.059 Å. The ligands are arranged in a nearly tetrahedral way around the Ti atoms. The bond angle at the bridging O atom is 171.8º.
    Notes: Bei der vorsichtigen Hydrolyse von (π-C5H5)2Ti(NO3)2 in Tetrahydrofuran entsteht der Zweikernkomplex [(π-C5H5)2Ti(NO3)]2O (A) Kristalldaten von A: monoklin, Raumgruppe P21/c; Gitterkonstanten: a = 12,656(4), b = 10,181(5), c = 16,197(3) Å, ß = 93,57(3)º und Z = 4. Eine Röntgenstrukturanalyse ergibt, daß die Nitratgruppen als einzähnige Liganden mit Ti—O-Abständen von 2,085 und 2,059 Å fungieren. Die Ti-Atome weisen eine annähernd tetraedrische Koordination auf. Der Winkel am Brücken-O-Atom beträgt 171,8º.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19814790813
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  • 7
    Electronic Resource
    Electronic Resource
    Über die Umsetzung von Adipinsäurediamid mit Phosphorpentachlorid (1973)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 396 (1973), S. 261-266 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Reaction of Adipic Acid Diamide with Phosphorus PentachlorideThe reaction of adipamide (I) with phosphorus pentachloride in a solvent leads to (Cl3P=NCCl2CCl2CH2)2 (II). The stages of the reaction are: 1. chlorination of the keto and methylen groups 2. formation of the —N=PCl3 group.This result is a supplement of the existing conception about the course of the reaction of carboxylic acid amides with phosphorus pentachloride.The reaction of (I) with PCl5 without any solvent has been reproduced and the course of reaction has also been investigated. This reaction gives mainly NC(CH2)4CN.The resulting product of a careful hydrolysis of (II) is (Cl2OPN=CClCl2CH2)2. A total hydrolysis gives back (I).
    Notes: Bei der Umsetzung von Adipinsäurediamid (I) mit Phosphorpentachlorid in einem Verdünnungsmittel bildet sich (Cl3P=NCCl2CCl2CH2)2 (II). Der Reaktionsablauf ist: 1. Chlorierung der Keto- und Methylengruppen und 2. Bildung der —N=PCl3-Gruppierung. Dieses Ergebnis ist eine Ergänzung der bisherigen Vorstellungen über den Reaktionsablauf bei der Umsetzung von Säureamiden mit Phosphorpentachlorid.Die Reaktion von (I) mit PCl5 ohne Lösungsmittel wurde nachgearbeitet und ebenfalls in ihrem Ablauf untersucht. Hierbei entsteht vornehmlich NC(CH2)4CN.Bei vorsichtiger Hydrolyse von (II) erhält man (Cl2OPN=CClCCl2CH2)2. Totalhydrolyse führt zur Rückbildung von (I).
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19733960303
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  • 8
    Electronic Resource
    Electronic Resource
    Ein Titan(IV)-Komplex mit zwei koordinativ gebundenen Wassermolekülen: [(π-C5H5)2 Ti(H2O)2](NO3)2 (1981)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 476 (1981), S. 62-68 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: A Titanium (IV) Complex with Two Coordinatively Bonded Water Molecules: [(π-C5H5)2Ti(H2O)2](NO3)2(π-C5H5)2Ti(NO3)2 and H2O react in acetone to form the diaquo complex [(π-C5H5)2-Ti(H2O)2](NO3)2 (A). An X-ray analysis shows the titanium atom to be nearly tetrahedrally coordinated. Mean values of distances: Ti—O 2.01 Å, Ti—Z 2.03 Å (Z = center of ring); angles: O—Ti—O 92.7°, Z—Ti—Z 133.6°. Anions and cations are joined by hydrogen bonds to form strands that run in the direction of the crystallographic a axis. A crystallizes in the orthorhombic space group Pnma with Z = 4 and lattice parameters at - 100°C a = 7.601(2), b = 13.458(4) and c = 13.139(4) Å.
    Notes: (π-C5H5)2Ti(NO3)2 reagiert mit Wasser in Aceton unter Bildung des Diaquokomplexes [(π-C5H5)2Ti(H2O)2](NO3)2 (A). Eine Röntgenstrukturanalyse ergibt, daß das Ti-Atom eine annähernd tetraedrische Koordination besitzt. Mittelwerte der Abstände: Ti—O 2,01 Å, Ti—Z 2,03 Å (Z = Ringzentrum); Winkel: O—Ti—O 92, 7°, Z—Ti—Z 133,6°. Die Anionen und Kationen sind entlang der kristallographischen a-Achse durch Wasserstoffbrücken zu Strängen verknüpft. A kristallisiert in der orthorhombischen Raumgruppe Pnma mit Z = 4 und den Gitterkonstanten bei — 100°C a = 7,601(2), b = 13,458(4) und c = 13,139(4) Å.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19814760508
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  • 9
    Electronic Resource
    Electronic Resource
    Das Verhalten der Elemente der III. Gruppe zueinander und zu den Elementen der IV. Gruppe (1948)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 256 (1948), S. 239-252 
    Details
    ISSN: 0372-7874
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1Es werden die Zustandsdiagramme von: Aluminium/Indium, Gallium-Thallium, Gallium/Silicium, Gallium/Germanium, Indium/Silicium, Indium/Germanium, Thallium/Germanium bestimmt.2Die von Valentiner und Mitarbeitern bearbeiteten Zustandsdiagramme des Indiums mit Thallium, Zinn und Blei werden, zum Teil auf Grund neuer Versuche, erörtert.3Es wird das Verhalten der Elemente der III. Gruppe zueinander wie zu den Elementen der IV. Gruppe besprochen. Es ergibt sich, daß die Elemente der III. Gruppe sowohl in der Tendenz zur Verbindungsbildung als auch in der Neigung zur Mischbarkeit ein Minimum aller Gruppen darstellen.4Es wird eine einfache Heizkamera beschrieben.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19482560404
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  • 10
    Electronic Resource
    Electronic Resource
    Abbau einiger Harnsäureglykol-äther durch Lauge (1925)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 58 (1925), S. 2740-2747 
    Details
    ISSN: 0365-9631
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19250581207
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