ISSN:
1432-2072
Keywords:
Isolation
;
Sex Differences
;
Chlordiazepoxide
;
Methylphenidate
;
Exploration
;
Locomotion
;
Rearing
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Effects of two doses each of chlordiazepoxide and methylphenidate on exploration, locomotion and rearing were observed in isolated and grouped male and female rats. Sex of the animals determined the effects of both drugs on rearing, and of chlordiazepoxide on preferences for the novel half of an exploration box. Drug administration seemed to abolish initial sex differences on the former response. Locomotion of isolated and grouped animals was also differentially affected by chlordiazepoxide. These findings emphasised the need to take genetic and environmental factors into account when considering the effects of psychotropic drugs on exploratory behaviour.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00429389
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