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  • 1
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    Urbana, etc. : Periodicals Archive Online (PAO)
    American Journal of Psychology. 90:4 (1977:Dec.) 621 
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  • 2
    ISSN: 1432-2072
    Keywords: Isolation ; Sex Differences ; Chlordiazepoxide ; Methylphenidate ; Exploration ; Locomotion ; Rearing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Effects of two doses each of chlordiazepoxide and methylphenidate on exploration, locomotion and rearing were observed in isolated and grouped male and female rats. Sex of the animals determined the effects of both drugs on rearing, and of chlordiazepoxide on preferences for the novel half of an exploration box. Drug administration seemed to abolish initial sex differences on the former response. Locomotion of isolated and grouped animals was also differentially affected by chlordiazepoxide. These findings emphasised the need to take genetic and environmental factors into account when considering the effects of psychotropic drugs on exploratory behaviour.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 29 (1973), S. 85-89 
    ISSN: 1432-2072
    Keywords: Lithium ; Social Isolation ; Spontaneous Activity ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Group-housed rats, injected with an acute dosage of 3 meq/kg lithium chloride, were tested on an activity platform either alone or in pairs 20 min or 3 h after drug administration. Contrary to previous findings, rats administered lithium were less active than those treated with saline after both post-injection periods. However the activity of the saline control animals tested alone after 3 h was considerably less than that exhibited by the same group after 20 min. This activity difference, which could be interpreted as a lithium-social or lithium-time interaction, is more simply explained in terms of the effects of the social isolation occuring between drug administration and testing.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 40 (1974), S. 91-99 
    ISSN: 1432-2072
    Keywords: Lithium ; Social Behaviour ; Sex ; Novelty ; Photographs ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Effects of lithium chloride on the social behaviour of male and female rats were measured in unfamiliar and familiar test situations using a photographic technique. Lithium-treated females showed an increase in body contact and a decrease in social distances in comparison with saline-treated controls in both test conditions. Males administered lithium showed increased corner occupancies in the novel test setting while in the familiar test they showed decreased body contact and increased average group social distance in comparison with the saline condition. Further tests in an exploration box confirmed that lithium decreased the general environmental responsiveness of male rats. The results are discussed with reference to the anti-aggressive effect of lithium.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 32 (1973), S. 81-84 
    ISSN: 1432-2072
    Keywords: Sociability ; Photographs ; Chlorpromazine ; Methamphetamine Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using a time-sample photographic method three measures of sociability showed, contrary to some previous findings, rats administered chlorpromazine (3 mg/kg) to be more sociable than those treated with methamphetamine (2 mg/kg) or isotonic saline. Saline animals were more sociable than amphetamine-treated subjects on two measures. This illustrative study demonstrates that variables influencing sociability results may include social conditions in the cage, post-injection and test environments, and the measure employed.
    Type of Medium: Electronic Resource
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