ISSN:
1432-2072
Keywords:
Lithium
;
Social Isolation
;
Spontaneous Activity
;
Rat
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Group-housed rats, injected with an acute dosage of 3 meq/kg lithium chloride, were tested on an activity platform either alone or in pairs 20 min or 3 h after drug administration. Contrary to previous findings, rats administered lithium were less active than those treated with saline after both post-injection periods. However the activity of the saline control animals tested alone after 3 h was considerably less than that exhibited by the same group after 20 min. This activity difference, which could be interpreted as a lithium-social or lithium-time interaction, is more simply explained in terms of the effects of the social isolation occuring between drug administration and testing.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00421214
