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  • 1
    Electronic Resource
    Electronic Resource
    A Case of Paracoccidioidomycosis: Experience with Long-Term Therapy (2000)
    Springer
    Infection 28 (2000), S. 119-120 
    Details
    ISSN: 1439-0973
    Keywords: Key words Paracoccidioidomycosis ; Therapy of paracoccidioidomycosis ; Mycosis ; Osteolysis ; Itraconazole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We describe long-term therapy for paracoccidioidomycosis occurring in a 61-year-old housepainter from Venezuela. The diagnostic examinations made in South America had shown pulmonary granulomatous lesions and an osteolytic pattern of the left knee that had been considered suspect of malignant disease with an indication for limb amputation. With the aid of fine needle aspiration biopsy (FNAB) and culture examination we diagnosed an osteomyelitis by Paracoccidioides brasiliensis and initiated therapy with itraconazole, 400 mg per day reduced to 200 mg per day after 2 months. At the end of 2 years of drug therapy, we observed complete regression of the pulmonary lesions and of the osteolytic area of the left knee. Moreover, we have periodically observed our patient to verify his clinical development and he is still in good health. We suggest that this pathology be considered in differential diagnosis of leprosy, tuberculosis, leishmaniasis, and systemic mycoses, even in non-endemic areas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s150100050060
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  • 2
    Electronic Resource
    Electronic Resource
    Hepatitis B virus infection among health care workers at an urban teaching hospital in southern Italy: A low occupational hazard? (1989)
    Springer
    European journal of epidemiology 5 (1989), S. 228-233 
    Details
    ISSN: 1573-7284
    Keywords: HBV infection ; Health care personnel ; Occupational hazard
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A prevalence study of HBV serologic markers was carried out among hospital employees of ten departments of the Second School of Medicine in Naples, an urban area with a high prevalence of HBV infection. Departments and occupational categories were selected to represent a spectrum of different exposure to B virus infection. Workers in a large electronic plant in the same geographical area were screened as controls. HBsAg prevalence was 4.8% in the hospital community and 4.0% in control group. It rises to 4.3% in the Campania Region, where all screened workers live, and in some specific areas of the same region it rises to 12%. But no significant difference among seropositivities for at least 1 marker of HBV, considered to be a better indicator of occupational hazard, was found among personnel of different departments or belonging to different occupational categories. None of the occupational and non-occupational risk factors studied was found to be significantly associated with HBV infection. Two years later, an incidence study was carried out among susceptible subjects. Seropositivity for 1 marker was 2.2% among hospital workers and 2.8% in the control group. These figures are lower than the annual attack rate (5%) required for an acceptable cost-benefit ratio of vaccination against hepatitis B. Our results indicate that in a geographical area with HBV endemicity the occupational hazard for B virus infection is low in hospital workers because of the high number of immunized subjects and the contacts with infected people out of the hospital.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00156836
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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