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  • Artikel: DFG Deutsche Nationallizenzen  (2)
  • Ca2+-ATPase activator  (1)
  • Key words Myelodysplastic syndromes  (1)
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  • Artikel: DFG Deutsche Nationallizenzen  (2)
Materialart
Erscheinungszeitraum
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  • 1
    Digitale Medien
    Digitale Medien
    Plakorin, a potent Ca2+-ATPase activator from the Okinawan marine spongePlakortis sp. (1989)
    Springer
    Cellular and molecular life sciences 45 (1989), S. 898-899 
    Details
    ISSN: 1420-9071
    Schlagwort(e): Sponge ; plakorin ; Plakortis sp. ; cyclic peroxide ; Ca2+-ATPase activator
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary A new cyclic peroxide, plakorin, which is a potent sarcoplasmic reticulum (SR) Caa+-ATPase activator has been isolated from the Okinawan marine spongePlakortis sp., its structure was elucidated on the basis of spectral data.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01954069
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
    Volltext
  • 2
    Digitale Medien
    Digitale Medien
    Refractory thrombocytopenia with chromosome 11q23 abnormality (1996)
    Springer
    Annals of hematology 73 (1996), S. 99-102 
    Details
    ISSN: 1432-0584
    Schlagwort(e): Key words Myelodysplastic syndromes ; Refractory thrombocytopenia ; Megakaryocytopoiesis ; Chromosome 11q23
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Although cytopenia is a common manifestation of myelodysplastic syndrome (MDS), isolated thrombocytopenia is rare. The term "refractory thrombocytopenia" (RTC) has been proposed as a counterpart of refractory anemia. We describe here a case of RTC associated with chromosome abnormality on 11q23. A 59-year-old man was admitted because of severe thrombocytopenia. A bone marrow examination revealed an increased number of micromegakaryocytes and the absence of normal-sized megakaryocytes without obvious dysplasia in either the myeloid or the erythroid lineage. A remarkable increase of GPIIb/IIIa (CD41a)-positive precursor cells in the bone marrow was observed. Cytogenetic examination detected the chromosome abnormality, an addition on chromosome 11q23. Translocation of the HRX gene was not detectable by Southern blot analysis. The diagnostic problems of isolated thrombocytopenia and possible participation of gene(s) on chromosome 11q23 in megakaryocytopoiesis as well as early hematopoiesis are discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s002770050209
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
    Volltext
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