ISSN:
1432-1920
Keywords:
Key words Toluene
;
Organic solvents
;
Magnetic resonance imaging
;
Iron
;
brain
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract MRI may be helpful in showing brain toxicity associated with chronic toluene inhalation. We report clinical and MRI findings over 3 years in a man with gradual neurologic decline secondary to toluene abuse. Cerebral atrophy most prominently involved the corpus callosum and cerebellar vermis. On T2-weighted images, loss of gray-white matter contrast, diffuse supratentorial white matter high-signal lesions, and low signal in the basal ganglia and midbrain were seen. In addition, MRI showed abnormal labor cortical low signal on T2-weighted images, most prominent in the primary motor and visual cortex. This cortical T2 shortening, not previously described in this condition, may reflect iron deposition.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002340050637
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