ISSN:
1435-1463
Keywords:
Keywords: Extrapontine myelinolysis
;
central pontine myelinolysis
;
parkinsonism
;
homovanillic acid
;
treatment.
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary. Extrapontine myelinolysis (EPM) is a demyelinating process of the brain. We report the case of an 11-year-old girl who developed EPM with parkinsonism. Magnetic resonance imaging revealed demyelinating patterns in the basal ganglia without central pontine lesions. The cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid were high at the time of onset and normalized upon complete recovery from extrapyramidal symptoms after a dopaminergic treatment. We speculated that demyelination of nerve fibers containing dopamine receptors in the striatum might be a main cause of these symptoms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s007020050215
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