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  • Magnetic resonance spectroscopy  (2)
  • Spinal cord compression  (2)
  • 1
    ISSN: 1432-1920
    Keywords: X-ray computed tomography ; Spinal cord compression ; Spinal osteophytosis ; Spinal nerve root
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In this study, the authors evaluate the importance of computed tomography (CT) in 15 patients who underwent surgical treatment for cervical disc disease. In nine operated on by an anterior approach, all CT examinations were interpreted as positive for disc herniation and correlated precisely with surgical observations. CT demonstrated protrusion of the disc, centrally in four and posterolaterally in five in all of whom disc material was found posterior to the vertebral body. Of six who underwent laminectomy, either thickening or calcification of the ligamentum flavum was demonstrated by CT and confirmed at surgery in five. Vacuum phenomenon in the intervertebral space and hypertrophy of the intervertebral joint were not infrequently associated. CT can exactly delineate cervical disc lesions and associated pathological changes.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1920
    Keywords: Cervical disc disease ; Myelography ; Spinal cord compression ; X-ray computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Herniated nuclear material of the cervical disc often perforates the posterior longitudinal ligament. Of 22 patients who were operated on by an anterior approach, 10 were of this type (the subligamentous type of cervical disc protrusion), while in the remaining 12 patients and 15 discs the protruded disc caused no tear in the ligament (the epiligamentous type). Myelography and CT myelography of these patients were reviewed. On CT myelography a localized and sharply demarcated excavation of the metrizamide ring was commonly found in the subligamentous type. Myelographic lateral view in this group shows a moderate or large indentation of the metrizamide column, since the herniated nucleus pulposus sometimes migrates caudally or cephalically. A small myelographic deformity coupled with diffuse excavation of the metrizamide ring on a CT myelogram leads us to the diagnosis of the epiligamentous type of cervical disc protrusion. In such cases, excision of the ligament is unnecessary during exploration of the discs, except when there is marked depression in the posterior longitudinal ligament. Presurgical recognition of both anatomical processes must be stressed for anterior discectomy.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1920
    Keywords: Magnetic resonance spectroscopy ; Brain tumours ; N-acetyl-aspartate ; Lactate ; Embolisation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We investigated metabolic changes in brain tumours following treatment, using proton magnetic resonance spectroscopy. In meningiomas, effective therapeutic embolisation led to an acute increase in lactate. In radiosensitive tumours such as malignant lymphoma, a decrease in lactate and in increase inN-acetyl-aspartate occurred after radiotherapy, which preceded changes observed on magnetic resonance imaging. On the other hand, no significant changes in spectral patterns were observed in malignant gliomas resistant to therapy. Tissue characterisation of brain tumours by spectral patterns on proton magnetic resonance spectroscopy remains controversial. However, we have shown it to be sensitive to metabolic changes following treatment, which may reflect the efficacy of the therapy.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1920
    Keywords: Key words Brain metabolism ; Cerebral infarcts ; chronic ; Magnetic resonance spectroscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The details of brain metabolism in chronic cerebral infarcts have not been clarified. Using proton MR spectroscopy (1H-MRS) at 1.5 T, we measured biochemical changes in 16 patients with large infarcts involving the motor cortex in the chronic phase (median 293.9 days) and related the findings to clinical data. Localised spectra were obtained using point-resolved spectroscopy, with an echo time of 270 ms. Regions of interest were placed on the frontal lobe, including the precentral gyrus and central sulcus. Motor function was assessed by the manual muscle power test at the time of the 1H-MRS study. Only three patients with severe paresis had no signal in the lesions and a lactate signal was obtained in 13 cases. N -acetyl aspartate (NAA) was observed in 4 cases with recanalisation of an occluded vessel. Motor function correlated strongly with the NAA/choline-containing compounds (Cho) ratio (P 〈 0.01) and lactate/Cho ratio (P 〈 0.01). We found various metabolic patterns, reflecting residual neurological function.
    Type of Medium: Electronic Resource
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