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  • 1
    ISSN: 1438-2199
    Schlagwort(e): Amino acids ; L-Ala ; Bacillus subtilis ; Spore ; Germination ; Alanine racemase
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Germination ofBacillus subtilis spores was initiated by L-Ala and competitively inhibited by D-Ala, suggesting the presence of an alanine receptor. The spores showed alanine racemase activity in the spore coat. To investigate the role of alanine racemase (L → D) on germination, net racemase activity was determined using diphenylamine as a germination inhibitor and germination was measured using D-penicillamine as a racemase inhibitor. Apparent affinity of L-Ala to the germinant receptor was more than 1000 times higher than that to the racemase. Germination increased in the presence of D-penicillamine, when the concentration of L-Ala was low and that of spores was high. Racemase activity was optimal at 65°C at pH 9.0 and germination at 43°C at pH 7.2. Under unfavorable growth conditions such as high population of spores in limited nutrients, high temperature and high pH, spore alanine racemase converted the germinant actively to the inhibitor and this conversion may regulate germination for survival of the population.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Journal of neurology 235 (1988), S. 489-490 
    ISSN: 1432-1459
    Schlagwort(e): Cheiro-oral syndrome, bilateral ; Pontine haemorrhage ; Medial lemniscus ; Ventral secondary ascending tract of the trigeminal nerve
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Cheiro-oral syndrome is a peculiar sensory disturbance observed around the corner of the mouth and the palm of the hand on the same side, usually occurring unilaterally. A male patient with bilateral cheiro-oral syndrome following pontine haemorrhage is reported. CT, MRI and neurological findings showed that the syndrome was due to a lesion in the medial lemniscus and ventral secondary ascending tract of the trigeminal nerve on both sides. Although unilateral cheirooral syndrome has been reported with a lesion in the parietal lobe, thalamus or brain stem, a bilateral syndrome could be caused only by a lesion of the brain stem.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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