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  • 1
    ISSN: 1435-1463
    Keywords: Melatonin ; oxazepam ; pinealectomy ; circadian ; diurnal ; brain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sham-operated and pinealectomized male rats were maintained at 14h light: 10 h dark cycles (lights-on 5.00 h) and injected daily, for 14 days, with oxazepam or vehicle.125I-melatonin binding was recorded in synaptosomes prepared at 10.00, 18.00, and 24.00 h from the hypothalamus, hippocampus and medulla-pons of the rats. In the sham-operated, vehicle treated rats, specific125I-melatonin binding in all brain areas studied was higher at 18.00 h, whereas in the oxazepam-treated animals, binding was higher at 24.00 h than at the other times tested. In the pinealectomized, vehicle-treated rats, the binding recorded at 18.00 h in all three brain areas, was lower than at the other times of day tested. Oxazepam treatment decreased125I-melatonin binding at 24.00 h in the hippocampus and medulla-pons of the pinealectomized rats and did not significantly affect the binding in the hypothalamus. These results indicate the ability of oxazepam, pinealectomy and their combination, to manipulate the diurnal variations in125I-melatonin binding sites in the rat brain.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neural transmission 95 (1994), S. 173-177 
    ISSN: 1435-1463
    Keywords: Melatonin ; antigonadotrophic ; prostaglandin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary PGE2 was shown to play an essential role in the gonado-inhibiting effect of melatonin in Syrian hamsters by transforming the neuroendocrine signal to gonadal reactivity. Prostaglandin is a vital link in the transduction of photoperiodic information into gonadal function and the difference in its levels brought about by melatonin given at different times of the day could explain the phenomenon why gonadal involution occurs only upon administration of melatonin towards the end of the day. It appears also that the melatonin signal is decoded in the pituitary, probably involving the short loop negative feedback of LH on LH-RH hormones.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Materialwissenschaft und Werkstofftechnik 19 (1988), S. 36-40 
    ISSN: 0933-5137
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Metal-matrix Composites with Metallic GlassesMetallic glass ribbons are well known for their very high tensile strengths. Since they offer an attractive potential of low-cost volume production, the development of a metallic glass-metal matrix composite should be very attractive. This paper reports first results on the feasibility of fabricating such composites by surface plating or incorporation by various techniques.The influence of fabrication methods on the interfacial bonding was investigated by means of cross-sectional light and electron microscopy.
    Notes: Metallglas-Bänder zeichnen sich durch sehr hohe Zugfestigkeit und kostengünstige Herstellung aus, so daß die Entwicklung eines Metallglas-Metallmatrix-Verbundwerkstoffes ausgesprochen interessant erscheint.Die vorliegende Arbeit berichtet über erste Ergebnisse, solche Verbundwerkstoffe durch Oberflächenbeschichten, verschiedene Einbettmethoden bzw. ein Festkörperreaktionsverfahren herzustellen.Dabei wird vorallem der Einfluß der Herstellungsmethoden auf die Grenzflächenhaftung licht- und elektronenmikroskopisch untersucht.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 66 (1994), S. 1179-1180 
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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