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  • Cushing's disease, inferior petrosal sinus sampling (IPSS)  (1)
  • Meningioma  (1)
  • PACS 25.43.+t Antiproton-induced reactions – 24.60.Dr Statistical compound nucleus reactions – 24.75.+i General properties of fission  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Raymond's syndrome following petrosal sinus sampling (1994)
    Springer
    Acta neurochirurgica 131 (1994), S. 157-159 
    Details
    ISSN: 0942-0940
    Keywords: Pituitary adenoma ; Cushing's disease, inferior petrosal sinus sampling (IPSS) ; Raymond's syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Inferior petrosal sinus sampling (IPSS) is used to evaluate the pituitary-dependency of Cushing's disease, and to predict the laterality of a microadenoma prior to transsphenoidal operation. A serious complication occured in a 14-year-old boy: he suffered brain stem ischaemia with abducens nerve palsy and hemiparesis (Raymond's syndrome). The case prompted us to reconsider the indication for this investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401467
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Gonadal steroid receptors in meningiomas (1987)
    Springer
    Journal of neurology 234 (1987), S. 328-333 
    Details
    ISSN: 1432-1459
    Keywords: Oestrogen receptor ; Progesterone receptor ; Androgen receptor ; Monoclonal antibody ; Meningioma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Oestrogen receptor (ER) analysis was performed in 70 meningiomas with an enzyme immunoassay, using monoclonal antibodies against human oestrogen receptor protein (oestrophilin) and with a sensitive radioligand binding assay, using 125I-oestradiol as radioligand. Low levels of ER immunoreactivity were found in tumours from 51% of patients, whereas ER binding activity was demonstrated in 40% of the meningiomas examined. In 8 (11%) tissue samples multiple binding sites for oestradiol were observed. The immunoreactive binding sites corresponded to the classical, high-affinity ER. In ligand binding studies, however, measurement of classical ER was considerably influenced by a second low-affinity, high-capacity oestrogen binding component even at low ligand concentrations. 3H-methylpromegestone and 3H-methyltrienolone, a synthetic gestagen and androgen, were used for concurrent determination of the progesterone receptor (PR) and androgen receptor (AR) binding activity. High concentrations of PR were detected in 53 (76%), whereas moderate levels of AR binding sites were demonstrated in 33 (47%) tumours. A positive correlation between ER immunoreactivity and AR binding activity is indicative for an oestrogen regulation of AR via the ER system. The presence of gonadal steroid receptors in a large proportion of meningiomas and the tendency for a dependence of receptor concentrations on the histological subtype could have implications for tumour therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00314289
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Neutrons produced by 1.22 GeV antiproton interactions with nuclei (2000)
    Springer
    The European physical journal 8 (2000), S. 197-204 
    Details
    ISSN: 1434-601X
    Keywords: PACS 25.43.+t Antiproton-induced reactions – 24.60.Dr Statistical compound nucleus reactions – 24.75.+i General properties of fission
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: Inclusive neutron energy spectra were measured by time of flight using 1.22 GeV antiprotons from LEAR, CERN, as projectiles and targets from natural Al, Cu, Ag, Ho, Ta, Au, Pb, Bi, U. The sum of two Maxwellian distributions was fitted to the spectra obtained at several forward and backward angles yielding neutron multiplicities Mi and slope or temperature parameters T i for the low-energy (evaporative, i=1) and high-energy (pre-equilibrium,i=2) parts, respectively. M 1 increases with A, proportional to the nuclear volume, and M 2 is growing with A , proportional to the nuclear radius. The T parameters are nearly independent of A. The results are compared with previous multiplicity measurements with a neutron detector, intranuclear cascade calculations and neutron spectra from stopped antiproton annihilation on nuclei. With the measured proton spectra also the ratio of emitted neutrons to protons was determined for Au.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100500070106
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    Paper (German National Licenses)
    Fulltext
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