ISSN:
1432-1440
Keywords:
Liver failure
;
Therapy
;
Nutrition
;
Encephalopathy
;
Ascites
;
Cholestasis
;
Renal failure
;
Gastrointestinal bleeding
;
Infection
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Chronic liver failure is characterized by the appearance of jaundice, ascites, encephalopathy and/or gastrointestinal bleeding. Acute episodes of hepatic decompensation are frequently precipitated by additional events, e.g. septicaemia, diuretic therapy or excessive protein intake. Identification, correction and treatment of these precipitating factors are first steps in the management of chronic liver failure. Nutritional support is important in the treatment of cirrhotic patients, because malnutrition is one of the major determinants of patient outcome. Management of encephalopathy reduces the appearance of gut-derived nitrogenous toxins and corrects imbalances in amino acid metabolism. Treatment of ascites is salt restriction supported by gentle and incremental administration of diuretics. Ursodesoxycholic acid has become a new and promising modality in the management of cholestatic liver diseases. If conservative therapy fails to recompensate liver function, liver transplantation may be indicated.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01795954
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