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  • 1985-1989  (2)
  • Oxalates  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 15 (1987), S. 105-108 
    ISSN: 1434-0879
    Keywords: Sodium ; Inhibitory activity ; Oxalates ; Phosphates ; Calcium ; Calculi
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary the effect of changes in urinary sodium, induced by dietary manipulation in normal subjects (NS) and in stone formers (SF) was studied by observing crytalluria qualitatively and by determining calcium, oxalate and phosphate crystallization quantitatively in an experimental model. In SF the calcium crystallization was significantly higher than in NS at all the three levels of urinary sodium studied. However, no difference was observed in oxalate and phosphate crystallization rates between these two groups. Calcium and oxalate (p〈 0.05) and oxalate and phosphate (p〈 0.001) were found to be correlated in NS but were non-significant in SF. The wide changes in the urinary sodium induced by dietary changes did not influence the crystallization rate of calcium, nor of oxalate and phosphate in NS as well as in SF. The results suggested that a sodium intake with lower and upper limits of 124 mg and 6,009 mg respectively did not act as “inhibitor” of crystallization rate nor did it induce hypercalciuria severe enough to pose a “risk” of stone formation. The results did not suggest that a high urinary sodium increases the solubility of calcium phosphate.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-0879
    Keywords: Ureteric stone formers ; Urine chemistry ; Oxalates ; Calcium ; Risk index ; Ion activity product
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Urine chemistry of 42 normal subjects (NS) and 59 ureteric stone formers (SF) from Jodhpur region of Rajasthan, India is presented. Twenty four hour urinary levels of calcium, oxalic acid and uromucoids were significantly higher and levels of magnesium, citric acid and inorganic phosphorus were significantly lower in SF as compared to NS. No significant difference was observed in the uric acid, sodium and potassium levels in the two groups. Significant correlation was observed between calcium and magnesium; calcium and oxalic acid; calcium and citric acid; magnesium and oxalic acid; and oxalic acid and citric acid in NS on the basis of mmol/l but not on the basis of mmol/24 h. Calcium and oxalic acid correlation was uninfluenced by magnesium and citric acid levels. The log of risk factor index (RI) was higher (p〈 0.001) in SF (−1.652) as compared to NS (−2.103). The log of ion activity product (IAP) was also higher (p〈 0.001) in SF (−3.192x10−3) than in NS (−2.914x10−1). Based on RI and IAP, a scale has been devised for the prediction of the risk of stone formation and recurrence.
    Type of Medium: Electronic Resource
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